Malignant Tumors Flashcards

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0
Q

Basal cell carcinoma (BCC)

A

Risk factors:

  • Fair complexion
  • Chronic sunlight exposure
  • Immunosuppression
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1
Q

Basal cell carcinoma (BCC)

A
Most common malignant skin tumor
>700,000 cases/year
Locally invasive 
Rarely metastasize 
M>F; 60 years
Head and neck
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2
Q

Basal cell carcinoma (BCC)

A
Papules or nodules
Smooth surface
Translucent;
Pearly, erythematous papules or plaques with rolled borders
Telangiectasia
Central ulcer
  - "rodent eaten"
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3
Q

Squamous cell carcinoma (SCC)

A
2nd most common malignant tumors
> 200,000 cases/year
May metastasize
Fair-skinned
UV
HPV
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4
Q

Squamous cell carcinoma (SCC)

A

High metastatic risk SCC

  • ears and lower lip
  • recurring rumors
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5
Q

Squamous cell carcinoma (SCC)

A
Flesh-colored to erythematous
Dry crusty
Smooth or warty surface
Ulceration
Firm
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6
Q

Basal cell carcinoma (BCC)

A

pearly

Telangiectasia

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7
Q

Melanoma

A
  • asymmetric macule with
  • irregular border and
  • color variations (red, tan, brown, or black)
  • most are greater than 6 mm in diameter
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8
Q

Melanoma

A
A - asymmetry
B - border
C - color
D - diameter
E - elevation or evolution
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9
Q

Superficial Spreading Melanoma

A
  • 70% of all melanomas in Caucasian
  • Change in pre-existing mole
  • Median age 37
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10
Q

Acral Lentiginous Melanoma

A
  • 50-70% of melanoma in African-Americans and Asians
  • Palm, sole or nail bed
  • median age 65
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11
Q

Prognosis

A

Depth is the most important prognostic factor:

- 3.60 mm, <50% five-year survival

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12
Q

Cutaneous T-Cell Lymphoma (CTCL)

A
  1. Mycosis fungoides (MF)

2. Sezary syndrome

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13
Q

Mycosis fungoides (MF)

A
  • Malignant clonal expansion of CD4+ cell

- uncommon (<1% of all lymphomas)

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14
Q

Sezary syndrome

A
  • 5% of all MF cases
  • Erythroderma
  • Circulating Sazery cells - atypical lymphocytes
    • Cerebriform nuclei
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15
Q

Paget disease

A
  • Intraductal breast carcinoma with retrograde extension

- unilateral eczematous areolar plaque