Acne Flashcards

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0
Q

Acne Tx

A
  • Topical retinoid (adaptelene gel) or systemic retinoid
  • Topical or oral Abx
  • Benzoyl peroxide

“Do not apply topic retinoids and benzoyl peroxide at the same time as benzoyl peroxide oxidizes retinoids. Alternating days if use both.”
2-3 months to see effect.

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1
Q

Acne pathogenesis

A
"Clogged pores"   = comedome
     Pores = pilosebaceous unit
Inflammation
Infection
   Bacteria- Propionibacterium acnes and granulosum
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2
Q

Acne Rosacea

A
Middle aged
No comedome
Flushing 
Facial nasal labia area
Papules and pustules superimposed on a background of Telangiectasias and general erythema
Rhinophyma - enlarged nose
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3
Q

Benzoyl peroxide

A
  • bA topic Meds with both antibacterial and comedolytic properties
  • Both Prescription and OTC
  • adverse effects
    • bleaching of hair, colored fabric, or carpet
    • may irritate skin; discontinue of severe
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4
Q

Topical or oral Abx

A

Tetracycline
Doxycycline
Minocycline

It takes 2-3 months to see improvement

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5
Q

Oral isotretinoin

A
  • For severe, nodulocystic acne failing other therapies
  • 5-6 months course
  • Teratogenic
    • female must be enrolled in FDA-mandated prescribing program in order to use this Meds
    • two forms of contraception must be used during the therapy and for one month after tx has ended
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6
Q

isotretinoin

A

Common side effects:

  • Xerosis (dry skin)
  • Cheilitis (chapped lips)
  • Elevated liver enzymes
  • Hypertiglyceridia
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7
Q

Open comedome

A

“Blackhead”

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8
Q

Closed comedome

A

“Whitehead”

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9
Q

Acne

A

“Pimples”

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10
Q

Acne Vulgaris

  1. Presence of hormones (androgens)
  2. Sebaceous gland activity
  3. Plugging of the hair follicle
  4. P. Acnes (Bacteria) in the hair follicles
A

Pathogenesis

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11
Q

Oral isotretinoin

A

Teratogenic

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12
Q

Spironolactone

A

Has anti-androgenic effects

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13
Q

Acne Rosacea

A

The absence of comedies helps to distinguish acne vulgaris from Rosacea

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14
Q

Acne

A

Adolescent

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15
Q

Acne

A

Predisposing factors

  • XXY chromosomal phenotype
  • Polycystic ovarian syndrome
  • Hyperandrogenism
  • Hypercortisolism
  • Precocious puberty