Male Reproductive Histology Flashcards
Tunica Albuginea:
- what does it do?
- converges to form what?
Leydig cells
- where are they located, close to what?
- what do they produce? what do they contain?
Seminiferous Tubules:
- central lumen lined by what?
- Epithelium surrounded by?
- what is found in between seminiferous tubules?
central lumen lined by a specialized stratified seminiferous epithelium containing somatic sertoli cells, spermatogenic cells
- epithelium is surrounded by a lamina propria, which is 3-5 layers of peritubular myoid cells. So it goes (out to lumen) Lamina propria, basement membrane, seminiferous epithelium.
- leydigs are found in between seminiferous tubules near blood vessels
what type of cells do the sertoli cells interact with
-types of nuclei in the seminiferous epithelium
at basolateral domain, sertoli cells have what type of junctions?
what does this create?
at basolateral domain, the sertolis have tight junctions creating basal and adluminal compartments
Basal compartment vs Adluminal compartment
Basal: spermatogonial cells are housed in niches, which allows for greater access to nutrients and signaling molecules
Adluminal compartment: tight junctions establish the blood-testes barrier, protects developing spermatocytes and spermatids from autoimmune reactions.
General organization of testis
which one is sertoli cell?
light purple shading with nucleus inside
Leydig cell androgen production:
Spermatogenic Cell sequence
- what arises from primordial germinal cell, what does it inititiate, what does it retain
- connection
Spermatogonia:
- ploidy
- location
- Type A vs Type B
directly responsive to testosterone, but not protected from autoimmune
Spermatogonia to spermatocyte
- type A does two things
- type B makes cells that enter meitosis in what stage and as what type of cell? what does this ensure?
- Spermatocytes are located where? where do their two meiotic divisions occur?
inside of blood testis barrier as in towards the lumen
mitosis outside of blood barrier, meiosis inside
Spermatocytes
- primary to secondary type of divison
- secondary type of division resulting in?
- end of meiosis I, vs end of meiosis II
Spermatids
- located where?
- round vs elongated location, timing
- process they are engaged in and what that entails
Spermiation:
what is it
- where does it occur
- residual bodies
- motile or not
- where do they go to continue maturation
Sperm Structure:
- mature sperm consist of what?
- head is basically what? capped by?
- tail’s pieces
Pieces of sperm tail:
- principal surrounded by what? what does this provide
- middle piece characteristics
- end piece contains what?
Sperm maturation pathway:
mature spermatids are transported through what?
efferent ductules are from the mesonephric ducts embryologically
Straight tubles:
- type of epithelium
- cells present
Rete testis: connect to?
- type of epithelium?
- wall formed by what?
Efferent Ductules:
- how many link rete to epididymis?
- ductule is lined with what?
Epididymis:
- parts
- lined with what epithelium and contains what branches?
- types of cells and their characteristics
- where are mature sperm stored
-Epididymis is covered by what?
Sperm maturation:
- how does it go from head to tail?
- time?
- what does it mean to be matured sperm
Vas Deferens:
lined by?
- parts of muscular wall?
- what is the part that leads into the prostate gland called?
- distal end receives what, and forms what?
Whart are the accessory genital glands?
Seminal Vesicle:
- dependent on?
- epithelium transitions from what to what?
- what does it secrete?
Prostate gland:
- empties into? via?
- zones of prostate gland?
The Penis:
- Erectile tissues
- surrounded by what?
-erectile tissue vascular sinuses supplied by what type of arteries
erection, what innervation, what happens to helicine arteries and vascular spaces
