Male repro 2 Flashcards
name the two components of the intratesticular duct system
- intratesticular
- extratesticular
components of the intratesticular duct system
-seminiferous terminus, straight tubules, rete testis
components fo the extratesticular duct system
- efferent ductules,
- duct of epididymis
- ductus deferens
what cell type is found in the seminiferous tubule terminus
-sertoli cells only
rete testis
- epithelium characteristics
- function
- simple cuboidal epithelium
- many microvilli
- fluid resorption to concentrate sperm
efferent ductules
- epith
- lumen characteristics
- function
- speudostratified columnar
- short cells with microvilli
- tall ciliated cells which transport the non-motile sperm
- star shaped lumen
- surrounded by smooth muscle
- resorbs most of the fluid from testis
- cilia are unique to the male repro tract
duct of the epididymis
- type of duct
- epithelium
- cell type found
- long coiled tube
- pseudostratified columnar
- principal cells
- basal stem cells
- smooth apical surface cells
principal cells of the epididymis
-tall and possess stereocilia
functions of the epididymis ducts
- absorb fluis and debris, residual bodies
- secrete products for sperm maturation (forward mobility protein )
- smooth muscle (1 layer proximally and 3 toward the tail)
- transit through tubules is about 12 days
- tail stores sperm prior to ejaculation
ductus (vas) deferens
- pseudostratified columnar with long microvilli
- basal (stem) cells
- single lumen not as smooth as epididymis ducts
- three smooth muscle layers that contract during ejaculation (LCL)
seminal vesicle
- tube type
- mucosa characteristic
- epithelium
- coiled tube
- highly infolded mucosa
- pseudostratified columnar with basal stem cells
secretions of the seminal vesicles
- fructose
- flavins (visible in UV light)
- prostaglandins
- seminogelins 1 and 2 (cause the semen to be viscous when initially ejaculated)
what types of contractions happen during ejaculation?
- smooth muscle
- 60% percent of the ejaculate comes from the seminal vesicles
prostate
- gland type
- epithelium
- what surrounds the glands?
- tubuloalveolar glands
- pseudostratified columnar
- fibrous stroma surrounds
prostate secretions
- characteristic
- type of exocrine release
- molecules
- alkaline fluid
- apocrine
- fibrinolysin (serine protease which liquifies the semun shortly after ejeaculation)
- citric acid
- zinc (inhibits wbc’s)
corpora maylacea
- form over time and are characteristic of prostate glands
- precipetates may clacify
- if enlarged it may block the ducts but this is normal
how can you detect prostate cancer
-prostate cancer cells do not express p63 which is extensively expressed in normal cells
four zones of the prostate
- central
- peripheral
- transitional
- periurethral
central zone of the prostate
-25% of the glans, resistant to carcinoma and inflammation
peripheral zone of the prostate
-70% of the gland, most of the carcinomas areise here; palpable by digital rectal exam
transitional zone of the prostate
-location of BPH: benign hypertrophy/hyperplasia proliferation of stromal andglandular tissue
periurethral zone of the prostate
-location of BPH
bulbourethral glands (of cowper) -secretions
- secrete alkaline mucus
- this is the pre ejaculate secretion
- neutralizes any residual urine in urethra
urethral glands (of Littre)
- where
- secretions
- function
- line the urethra
- mucous producing
- protect urethra from urine
erectile tissue
- consists of
- vessels
- fibromuscular CT
- contains cavernous spaces
- contains helicine arteries with valve-like intima cushion
helicine arteries of the erectile tissue
- have a valve-like intima cushion
- smooth muscle cushion relaxes (permitting blood flow where it enters the cavernous spaces) following NO release from parasympathetic NS and subsequent cGMP production
- cavernous spaces fill with blood sufficiently to compress venus plexus leading to erection
