Cardiovascular Flashcards

1
Q

tunica intima

A
  • lines the lumen
  • endothelial cells
  • underlying CT
  • inner elastic lamina
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2
Q

tunica media

A
  • smooth muscle
  • elastic lamina
  • elastic fibers
  • external elastic lamina
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3
Q

tunica adventitia

A
  • CT
  • blood vessels
  • nerves
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4
Q

vessel components made by smooth muscle

A
  • inner elastic lamina
  • elastic lamina
  • elastic fibers
  • external elastic lamina
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5
Q

artery shape

A
  • thick wall

- circular

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6
Q

vein shape

A

-thin wall, less circular

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7
Q

elastic arteries

A
  • large variation in size
  • typically over 10mm OD
  • contain fenestrated elastic lamina in tunica media
  • reduce pulsatile flow
  • contain blood and nerve supply
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8
Q

muscular arteries

A
  • large variation in size
  • typically 10-40 layers of SM
  • contain inner elastic lamina (IEL)
  • contain external elastic lamina when large
  • reduce pulsatile flow
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9
Q

small arteries

A
  • usually 3-10 layers of smooth muscle
  • inner elastic lamina in large ones
  • smooth muscle wraps around the artery, the endothelial cells are arranged longitudinally
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10
Q

veins will not have…

A
  • IEL or EEL

- flow is not pulsatile

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11
Q

arterioles

A
  • microcirculation
  • usually contain less than 3 layers of smooth muscle
  • no elastic laminae
  • most commonly associated with accompanying venule
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12
Q

capillaries

A
  • microcirculation
  • consist of endothelial cells and basal lamina
  • no tunica media
  • no T adventitia
  • usually 4-10 um n diameter (just large enough for RBC’s to pass through)
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13
Q

continous capillary

A

-found in nervouse tissue, muscle and CT

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14
Q

fenestrated cap

A

-typically found in endocrine glands and kidney glomerulus

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15
Q

pericytes

A
  • lie within capillary basal lamina
  • regulate capillary permeability (blood brain barrier)
  • contractile
  • help control endothelial proliferation
  • communicate via gap junctions
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16
Q

venules

A
  • endothelial cell wall
  • no t media
  • no T adventitia
  • ususally 10-50nm in diameter
  • leaky (most lymph and white blood cells exit here)
  • histamine sensitive
17
Q

small/medium veins

A
  • endothelial cell wall
  • smooth muscle in T media
  • thick T adventitia
  • usually 0.1-10mm in diameter
  • have valves (in extremities)
18
Q

large veins

A

-longitudinal bundles of smooth muscle in tunica adventitia
-elastic fibers also present
-

19
Q

portal system

A
  • arteris enter in the digestive tract
  • capillaries of the digestive tract found in stomach, intestines, pancreas, and spleen
  • hepatic portal vein carries the nutrients picked up here into the liver
  • then the hepativ vein leavs the liver to meet back up with inferior vena cava
20
Q

heart wall from most innner to most outer

A
  • endocardium (tunica intima)
  • myocardium (tunica media)
  • visceral pricardium (epicardium, tunica adventitia)
  • pericardial cavity
  • parietal pericardium
21
Q

endocardium

A

-contains purkinje fibers (conduction myocytes)

-

22
Q

coronary arteries found in…

A

-epicardium

23
Q

atherosclerotic placque

A
  • focal thickening of intima
  • ECM
  • macrophages with lipid (foam cells)
  • SMC’s with lipid
  • cholesterol deposits
  • prone to induce clotting
24
Q

complications of atherosclerosis

A
  • myocardial infarction
  • angina
  • conductive anomalies (eg arrhythmias)
25
Q

histamine release during inflammation causes

A

-increased vascular permeability (edema)