Malaria--Krafts and Regel

Question 1

What is the vector for the malaria parasite?

Answer 1

Anopheles mosquito

Question 2

P. falciparum

Answer 2

most deadly

can infect any RBC stage

most common in Africa

not many relapses

Question 3

P. vivax

Answer 3

most common outside of Africa

relapses

mild anemia

Question 4

P. ovale

Answer 4

• relapses
• not common

Question 5

What does Plasmodium go upon infection?

Answer 5

liver

Question 6

Stages of maliral infection

Answer 6

Sporoid (entry)

Schizont (lots of babies)

Merazoites (infect red cells)

Question 7

Enlarged red cells

Schuffner’s dots

Answer 7

• P. ovale*
• P. vivax*

*also the ones that cause relapse

Question 8

What form inside the RBC of the malarial parasite is the most important to remember?

Answer 8

ring

Question 9

Rosettes are formed by…

Answer 9

P. falciparum

Question 10

How do roses kill children?

Answer 10

rosettes of P. falciparum

knobbing out of RBCs

clot

cerebral ischemia

death

Question 11

P. falciparum proxysm

Answer 11

24 hr

Question 12

P. vivax or ovale paroxysms

Answer 12

every 48 hours

Question 13

P. malariae paroxym

Answer 13

every 72 hours

Question 14

Which organism uses antigenic variation?

Answer 14

P. falciparum

2% of each new generation

Question 15

Gold standard test for Plasmodium

Answer 15

blood smear

*quick tests can be used in the field

Question 16

These two forms lay latent in the liver

Answer 16

P. vivax and ovale

Also cause relapses every 48 hours

Question 17

What form of the malarial organism is killed by drugs?

Answer 17

erythrocytic stages

Question 18

What is the “radical cure”

Answer 18

primaquine

kills non-erythrocytic stage of infection