malaria Flashcards
1
Q
malaria
A
- protist
- plasmodium
2
Q
M mode of transmission
A
- indirect
- vector = female anopheles mosquito
- humans are infected when bitten by an infective female mosquito
- only anopheles mosquitos can transmit
- also transmitted by blood transfusion, organ transplant, and shared needles contaminating blood
3
Q
M geographical distribution
A
- tropics
- sub - saharan africa
- asia
- south america
- warm wet areas
4
Q
M impact on host / symptoms
A
- parasitizes the human liver and red blood cells
- attack begins with chills, fever and sweats
- after 10 days: vomiting, diarrhea, headaches, stomach aches, weakness
- if left untreated seizures, mental confusion, kidney failure, coma, brain damage, death
- symptoms are due to bursting red blood cells and clogged capillaries to major organs
5
Q
M economic importance
A
- sick adults are unable to work leading to low productivity not being able to produce enough food for their families
- they then remain poor with little food to eat leaving them more vulnerable to disease
- tourists are less likely to visit so less revenue for their country
- very expensive
- hospital care
6
Q
M diagnosis
A
- blood smear, microscopy exam
- rapid immune tests detect antigens
7
Q
M treatment
A
- antimalarial drugs kill the plasmodium and stop them from spreading
8
Q
M prevention
A
- wear loose clothing
- sleep in bed nets - cheap and effective
- insecticides - expensive and pollute environment
- mustard seeds in pond to drag larvae down and drown them
- if prescribed antimalarial drugs takes strictly as directed
- be aware of malaria risk zones
9
Q
M life cycle
A
- sporozoites
- infected mosquito bites a person, injecting parasites, sporozoites into the blood
- sporozoites move into the blood and travel to the liver
- they multiply through asexual reproduction in the liver cells to form merozites - merozites
- burst from liver into the blood
- they invade red blood cells and multiply until the red blood cells burst releasing merozites to invade other red blood cells and release toxins causing symptoms of malaria - merozites turn into gametocytes
- mosquitos suck as infected human and swallow gametocytes that fuse and mature into gametes
- gametes fuse to form zygote which matures into an ookinete which divides asexually to form sporozoites
- sporozoites leave the mosquitos intestine and move into the salivary glands