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PUBHLTH 370 Final > Malaria > Flashcards

Malaria Flashcards

1
Q

Vector

A

Female anopheles mosquito

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2
Q

Parasite

A

Protozoan known as plasmodium parasite

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3
Q

Latent

A

Mosquito bite to first symptoms

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4
Q

Incubation

A

Onset of infection to symptoms

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5
Q

Serology

A

Antibody detection

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6
Q

Elimination

A

Interruption of local transmission on specified malaria parasite

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7
Q

Eradication

A

Permanent reduction to zero

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8
Q

Uncomplicated malaria

A

Flu like symptoms

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9
Q

Complicated malaria

A

Seizures, coma, respiratory distress, kidney, liver failure

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10
Q

Etiology

A

One of the oldest human diseases, most deaths are in children under 5 in Africa, you cannot be immune from the infection, malaria = endemic (regular occurance) in all countries

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11
Q

Vector

A

Female anopheles mosquito, bite blood for heme (iron containing compound in hemoglobin)

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12
Q

Cycle - pre erythrocytic phase

A
  1. mosquito bites human
  2. sporozoites enter liver
  3. replication
  4. liver cells rupture and merozoites they get released
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13
Q

Cycle - blood stage

A

**known as sexual cycle
1. merozietes produce gametocytes

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14
Q

Cycle - phase in mosquito

A
  1. mosquito ingests gametocytes via bite
  2. gametocytes mate and undergo meiosis
  3. migrates and forms oocyst
  4. sporozoites develop
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15
Q

Public health interventions

A

Vaccinations via mosqurix however it is not efficient, pharmacologic preventative treatment

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16
Q

Diagnostic testing

A

For a current infection: smear microscopic of blood, PCR, antigen detection, for a past infection: serology or an antibody detection

17
Q

Sporozoites

A

Responsible for the initial infection of a host

18
Q

Merozoites

A

Break out of liver and enter ones bloodstream

19
Q

Gametocytes

A

Cells that become gametes in the life cycle of malaria

20
Q

Oocyst

A

A cyst containing a zygote

PUBHLTH 370 Final (7 decks)

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