Malaria Flashcards

1
Q

epidemiology of malaria

A
Americas
western pacific
eastern
Mediterranean
south-east Asia
Africa (most cases)
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2
Q

lifecycle of malaria

A

during the bite, the saliva of the mosquito is injected to the body

along with the malaria parasite within

malaria will travel to liver through the bloodstream

inside the liver, malaria will enter the liver cells through kupffer cells and killing 1 or more livercells

multiply in the liver cell and burst into the blood stream

new strain of malaria goes in to RBC and multiply and cause the RBC to be sticky

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3
Q

symptoms of malaria

A
headache
fever
fatigue
muscle pain
back pain
chills
sweating
dry cough
enlarge spleen
nausea
vomiting
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4
Q

estimated risk of malaria

A

3.2 billion ppl where 1.2biliion are at high risk

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5
Q

what can be use to malaria prevention

A

doxycycline - up to 2 years

atovaquone with proguanil hydrochloride - up to 1 year

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6
Q

when is dichloro-diphenyl-trichloroethane developed

A

developed as an insecticides in the late 1940s

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7
Q

how does the quinine used to treat malaria

A

kill the parasite or preventing it from growing (plasmodium falciparum)

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8
Q

what’s the reserved for intravenous treatment of severe malaria

A

Quinine

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