Main types of antibiotics Flashcards
Metronidazole
GET
treats Giardia, Entamoeba, Trichomonas (vaginitis)
antibacterial and Antiprotozoal agent
-forms toxic free radical metabolites in the bacterial cell that damages DNA
what is trimethoprim?
describe its mechanism of action
“Try me”😎>> nvr mind i got a UTI -.-
Used in combination with Sulphonamides
-treatment of UTI,shigella, salmonella, it interferes w/ folic acid synthesis, which is responsible in NUCLEIC ACID synthesis.
side effects: megoblastic anemia, leukopenia, granulocytopenia
(TMP= Treats Marrow Poorly)
**A potent inhibitor of bacterial dihydrofolate reductase. Leading to a decreased availability of the tetrahydrofolate cofactors required for purine, pyrimidine, and amino acid synthesis
Vancomycin
Glycopeptide!
effective against multidrug resistent organisms!
Be aware: if weyre trying to treat staph aureus!( which is in the blood stream) We give it to them IV
but in Cdiff>> give them orally!
what do the terms Bacteriostatic and bacteriosidal mean WHEN ADMINISTERING A DRUG?
Bacteriostatic= Inhibit the growth of the bacteria (then immune system finsihes the dirty work)
Bacteriosidal= KILL the bacteria in the presence of an ineffective immune system
GIVE BACTERIOSTATIC ONLY IN SOMEONE WITH AN EFFECTIVE IMMUNE SYSTEM!
Ceftriaxone
under what class?
(lies under Cephalocporin class)
B-lactam drugs that inhibit cell wall synthesis
Gram -
has good activity in the CSF
-MENINGITIS, Gonirrhea, disseminated lyme disease
Flucloxacillin
– Active against staphylococci & streptococci
Must know this!
its quite cocky!
flucloxacillin has activity against beta-lactamase-producing organisms such as Staphylococcus aureus[
Penicillin mechanism
inhibits cell wall synthesis
by inhibiting cross links of peptidoglycans!
flucloxacillin vs Penicillin
– Mainly active against streptococci >> Penicillin
-– Active against staphylococci & streptococci >Flucloxacillin
microbial therpy summary
List 4 indications for Tetracycline use
Non-pneumonic chest infections
Skin/soft-tissue infection with penicillin allergy
Chalmydia
Pelvic Inflammatory Disease
which antibiotic class inhbits cell wall synthesis by inhibiting peptidoglycan cross linking?
Cepaholsphorins, pencillins, carbapenems
Fluconazole
“i went to Canada and got a Flu”
Inhibit cell-membrane synthesis
to treat Candida
can be used orally and IV
used for oral and vaginal thrush
can be used also in imuunocompirompised patients
What do we give against Influenza A & B ?
What is aciclovir?
Antiviral agent used for herpes and varicella zoster.
Active in atypical pathogens in pneumonia
– Active against chlamydia & some protozoa
– Shouldn’t be given to children <12 years
name the antibiotic Tetracycline & doxycycline
Amoxillin?
If u have cellulotis and u dint know what the cause is what anitbiotic do u give?
what does this amntibiotic do?
Flucoxcillin
U had a UTI infection whith this strain shown?
what is the bacteria? What tyore? How do u treat it? Mechanicsm of acrion
Gram negative bacillii
This is a case of tonsilitis!>> what bacteria causes it? How do u treat it? What is the emchanism of axtion
