Magnesium sulfate

Question 1

Magnesium sulfate side effect

Answer 1

ALOC
Hypotension
Heart block
Hypocalcemia

Question 2

Magnesium sulfate dose

Answer 2

Adult

• Torsades de pointes: 1 – 2g IVP over 1 – 2 minutes
• Eclamptic seizure: 4 – 5g IVP concurrently with up to 5g IM in each buttock then 4 – 5 g every 4 hours
• Bronchodilation: 2g IVP

Pediatrics

• Torsades de pointes: 25 – 50mg/kg/dose max dose of 2g
• Bronchodilation: 25mg/kg/dose max 2g

Question 3

Magnesium sulfate action

Answer 3

Magnesium sulfate acts as a physiological calcium channel blocker, CNS depressant and
anti-convulsant. It depresses the function of smooth, skeletal and cardiac muscles

Question 4

Magnesium sulfate class

Answer 4

Electrolyte

Question 5

Magnesium sulfate indication

Answer 5

Hypomagnesaemia
Torsades de pointes
Eclamptic seizure
Adjunctive treatment in moderate to severe acute asthma

Question 6

Magnesium sulfate contraindication

Answer 6

Hypocalcaemia
Heart block
Myocardial damage
Anuria