magnesium Flashcards

1
Q

how abundant is magnesium in the body

A

its the 4th most abundant mineral in the body. 54% in skeleton, 45% in soft tissue

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2
Q

what are the functions of Mg

A

bone mineralization, cofactor (metalloenzyme), muscle relaxation

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3
Q

magnesium is found with in what two forms in bone mineralizaion

A

70% crystal lattice, 30% in amorphous structur

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4
Q

what is the most common enzyme magnesium is a cofactor for

A

mostly kinase which uses ATP or ADP

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5
Q

magnesium is required for the metabolism of

A

carbs, lipids, proteins, fat, protein and dna synthesis

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6
Q

what does magnesium stabilize?

A

Mg stabilizes ATP

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7
Q

what is the role of magnesium in muscle relaxation?

A

it is a calcium-channel blocker

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8
Q

what vitamin does magnesium activate

A

Vitamin D

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9
Q

is magnesium required for PTH secretion

A

yes

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10
Q

magnesium RDA or men

A

males 19-30=400mg >30=420mg

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11
Q

magnesium RDA for female

A

female 19-30=310mg

>30=320mg

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12
Q

good sources of magnesium

A

Seeds, nuts, grains, legumes, dark green leafy veggies

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13
Q

moderate sources of magnesium

A

milk, tofu plant products > animal prodcts

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14
Q

magnesium deficiency

A

nausea, vomiting, muscle weakness, tremors personality change, tetany (hypocalcemia and hypokalemia usually precedes

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15
Q

acute depletion of magnesium=

A

renal disease, hyperthyroidism, pancreatitis, protein insufficiency, diabetics, PTH disorders

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16
Q

moderate depletion of Mg=

A

elderly

17
Q

TUI from non food sources for Mg

A

350mg/d

18
Q

whos is at risk of Mg toxicity

A

patients with kidney disease because it is the main regulator of Mg levels

19
Q

symptoms of magnesium toxicity

A

diarrhea, nausea, flushing, slurred speech, migraine

20
Q

hypermagenesemia physical findings

A

loss of deep tendon reflex, muscle weakness, hypotension, vasodilation, arrhythmia, skeletal muscle paralysis, cv failure, coma death