M1: Bacteriology Flashcards
Allows chromosome replication, transcription and translation to be tied together. Inhibition of any one of them affects the others to a greater degree.
Lack of nuclear membrane
The _______ size of prokaryotes allows them to enter smaller spaces. It also means that cells have a smaller chromosome.
Smaller
Is a single circular genome
Bacterial chromosome
Are very important to relieve stress on the structure and to maintain its function
Topoisomerases
Having only one copy of each genome
Haploid genome
Lack organelles but this does not have a big effect on bacterial infection and treatment
Prokaryotes
Provides an excellent target for antibacterial drugs
Ribosomes 70s
Maintains a membrane potential to drive ATP synthesis and other functions
Bacterial membrane
Prokaryotic membrane has this which make it susceptible to polymyxin action.
Phospholipids
Important for promoting adhesion which allows the bacteria to attach and maintain their location in the body
Pili
The thickness of the __________ membrane facilitates its identification by the gram stain by trapping stain.
Gram positive
Is only a single layer thick and the stain washes away during the procedure, requiring use of a counterstain.
Gram-negative peptidoglycan
Present in the outer membrane is the most potent activator of innate and immune host cell functions of any cell wall components can induce fever and sepsis.
LPS
Are more likely to cause fever and sepsis
Gram negative bacteria
_________ prevents and ________ limits access of the complement membrane attack complex from the membrane surface.
Peptidoglycan & O Antigen
