Lymphome non Hodgkinien Flashcards

1
Q

Facteurs de risque de LNH ?

A

Agents infectieux

  • -> VIH, EBV, HTLV-1, VHC, HHV8
  • -> Hélicobacter pylori
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2
Q

Marqueurs lymphocytes B ?

A

CD20

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3
Q

Marqueurs lymphocytes T ?

A

CD3

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4
Q

2 types de LNH les plus frequents

A
  • Lymphomes folliculaires

* Lymphomes diffus à grande cellules

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5
Q

Cytogénétique

–> Lymphome folliculaire

A

t(14;18)

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6
Q

Cytogénétique

–> Lymphome du manteau

A

t(11;14)

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7
Q

Cytogénétique

–> Lymphome Burkitt

A

t(8;14)

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8
Q

Lymphomes très agressif ?

A

Burkitt

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9
Q

Lymphomes agressifs ?

A
  • Lymphome B diffus à grandes cellules

* Lymphomes T

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10
Q

Lymphomes intermédiaires ?

A

Lymphomes du manteau

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11
Q

Quels sont les 2 index pronostic ?

A

• FLIPI
–> Pour les lymphomes indolents

• IPI
–> Pour les lymphomes agressifs

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12
Q

Entre FLIPI et IPI, lequel prend en compte l’hémoglobine ?

A

FLIPI

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13
Q

Quel est le principal effet secondaire du Rituximab ?

A

• Syndrome de relargage de cytokines
–> Fièvre

  • Erythème cutané
  • Hypo ou hyper tension
  • Dyspnée

==> Régresse à l’arrêt de la perfusion
==> Ne contre-indique pas la reprise du TTT

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