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Haematology SOH > Lymphoma > Flashcards

Lymphoma Flashcards

1
Q

Clinical features

A 
Lymphadenopathy 
Night sweats 
Weight loss 
Itch without rash 
Alcohol induced pain at site of lymph nodes 
Fatigue
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2
Q

Investigations

A

Lymph node biopsy

  • by a surgeon.
  • FNA and core needle biopsy are often insufficient to make the diagnosis as a large sample is needed to assess the architecture of the lesion
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3
Q

Lymphoma can be diagnosed by CT scan. True or false?

A

False

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4
Q

What kind of investigation confirms the presence of a lymphoma

A

Immunohistochemistry on the lymph node biopsy

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5
Q

What are the 2 broad categories

A

Hodgkin’s

Non hodgkin’s

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6
Q

Sub types of non-hodgkins lymphoma

A

T cell

B cell

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7
Q

What is the most common subtype of non-hodgkin lymphoma - T cell or B cell?

A

B cell (90%)

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8
Q

T cell non hodgkin lymphoma - what is the most malignant ?

A

Precursor T-ALL, lymphoblastic lymphoma

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9
Q

B cell non hodgkin lymphoma - what is the most malignant

A

Precursor B-ALL

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10
Q

Burkitts lymphoma is

  • hodgkins
  • T cell non hodgkins
  • B cell non hodgkins
A

B cell non hodgkins

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11
Q

Burkitts lymphoma is very aggressive. True or false?

A

True

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12
Q

Burkitts lymphoma grows slowly. True or false?

A

False

- grows rapidly

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13
Q

Mantle cell lymphoma - grows rapidly. true or false

A

True

- looks low grade under the microscope

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14
Q

Mantle cell lymphoma is

  • hodgkins
  • B cell non hodgkins
  • T cell non hodgkins
A

B cell non hodgkins

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15
Q

Reed sternberg cell is seen in which type of lymphoma

A

Hodgkins lymphoma

- looks like an owl

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16
Q

Which is most common

- hodgkins or non hodgkins lymphoma

A

Non-hodgkins

17
Q

What type of lymph node biopsy to diagnose lymphoma

A

Excisional biopsy

- NOT FNA

18
Q

What is the bimodal distribution of hodgkins lymphoma

A

20-30

then 50-60

19
Q

Which is more localised - hodgkins or non-hodgkins lymphoma

A

Hodgkins lymphoma

Haematology SOH (22 decks)

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