Cytotoxic chemotherapy Flashcards
1
Q
Cell cycle specific agents - duration of exposure is more important than dose. True or false?
A
True
2
Q
Name 2 types of cell cycle specific agents
A
Anti-metabolites
Mitotic spindle inhibitors
3
Q
Anti-metabolites - which one inhibits dihydrofolate reductase?
A
Methotrexate
4
Q
Mitotic spindle inhibitors - name 2 examples
A
Vinca alkaloids
Taxotere (Taxol)
5
Q
Non-cell cycle specific agents - cumulative dose is more important than duration. True or false?
A
True
6
Q
Non cell-cycle specific agents - name 3 examples
A
Alkylating agents
Platinum derivatives
Cytotoxic antibiotics
7
Q
Non cell-cycle specific agents - platinum derivatives - name 2 examples
A
Cis-platinum
Carboplatin
