Lymphatic System Red Stuff Flashcards
Lymphatic System Functions
Fluid Balance, Fat Absorption, Defense
water plus solutes from plasma and cells
lymph
4 steps of movement through lymphatic vessels
contraction of lymphatic vessels, skeletal muscle contraction, one-way valves, thoracic pressure changes
the only place to filter lymph
lymph nodes
drains the right side of the body
right lymphatic duct
drains the entire body except the right head, upper limb, and right thorax
thoracic duct
the primary lymphatic organs where lymphocytes become immunocompetent is
red bone marrow and thymus
the secondary locations where lymphocytes interact
organs/tissues
B and T cells are found here
lymphocytes
differentiated monocytes that phagocytize damaged cells
macrophage
antigen presenting cells
dendritic cells
3 groups of tonsils
palatine, pharyngeal, lingual
the section of a lymph node where substances removed by phagocytosis or stimulate lymphocytes to proliferate in
germinal centers
functions of the spleen
destroy defective RBC’s, detect and respond to foreign substances, limited reservoir for blood
main things to know about the thymus
Decreases in size after 60 years (atrophy), maturation of T cells
the spleen filters _____ and is where lymphocytes respond to _______
blood, infections
what are the two categories of immunity?
innate, adaptive
this immune response produces the same response every time
innate
what are the methods within the innate response?
physical barriers, chemical mediators, cells
this immune response can be changes based on the specific pathogens
adaptive
what are the methods of the adaptive response?
specificity, memory
what are the chemical mediators within innate immunity?
cell surface mediators, inflammatory mediators, cytokines
cell surface mediators include:
lysozymes, mucus, sebum
inflammatory mediators include:
histamine, complement, eicosanoids
this type of chemical mediator regulates the intensity and duration of immune responses and stimulates the proliferation/differentiation of cells
cytokines
part of the inflammatory mediators, this is a group of 20 proteins that circulate in the blood in inactive form
complement
complement can be activated during the ______ pathway of the innate immunity, and the ______ pathway in adaptive immunity.
Adaptive immunity path requires what?
alternative, classical
antibodies
activated compliment has what two functions
form membrane attack complexes, promote inflammation
a type of cytokine that protects against viral infections and some cancers
interferons
through __________ _________interferons act as a warning signal as they are produced by infected cells, but cause nearby cells to produce antiviral proteins
paracrine signaling
interferons activate _____ and ______ that attack tumor cells
macrophages and natural killer cells
