Lymphatic system Flashcards

1
Q

What are the 3 functions of the lymphatic system?

A
  1. draining interstitial fluid.
  2. transporting dietary lipids
  3. protection
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2
Q

What is lymph?

A

interstitial fluid collected by lymph capillaries.

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3
Q

What are the 2 major lymphatic ducts?

A

Thoracic- 3/4 of the body.

right lymphatic duct-right arm and right side of upper torso

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4
Q

Where do these ducts empty into the circulating system?

A

subclavian vein

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5
Q

where would you find the cistern chyli

A

bottom end of thoracic duct

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6
Q

what are the primary organs of the lymphatic system?

A

red bone marrow and thymus gland

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7
Q

what are the secondary organs of the lymphatic duct?

A

lymph nodes, lymph nodules, spleen

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8
Q

describe the structure and the function of a lymph node.

A

made of a capsule, cortex, medulla. provide biological filtration

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9
Q

What does albumin do for the blood?

A

maintains osmotic pressure

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10
Q

what happens when the flow of lymph is blocked?

A

edema

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11
Q

What are lacteals and what do they do?

A

specialized lymphatic capillaries in villi of small intestine that transports lipids

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12
Q

What are lymph nodules?

A

follicular dendritic cells found in the cortex

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13
Q

what is MALT? what are peyer’s patches?

A

mucosa associated lymphoid tissue. Lymph nodules found in ileum

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14
Q

What are tonsils? 3 major tonsils?

A

lymphoid tissue under the mucous membranes of the throat. 1. palatine. 2. pharyngeal 3. lingual

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15
Q

What does the thymus do? Where is it located?

A

in mediastinum above the heart. produces thymosin-aids in maturation of T-cells

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16
Q

What is the white pulp of the spleen? Red pulp?

A

largest of the lymph organs, the spleen has white pulp-mostly b cells (islands) and red pulp-venous sinuses

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17
Q

What are the functions of the spleen?

A

blood formation, blood filtration, and platelet storage

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18
Q

What is resistance?

A

ability to ward off disease

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19
Q

What is susceptibility?

A

lack of resistance

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20
Q

What lowers skin pH

A

lactic acid

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21
Q

What is lysozyme?

A

enzymes that damage bacterial cell walls.

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22
Q

How do transferrins prevent microbe growth?

A

tie up free iron

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23
Q

What is compliment?

A

10-20 normally inactive proteins that when activated, enhance certain immune reactions. (activate inflammation, opsonization, cytolysis

24
Q

How does fever help the body fight off infection?

A

causes liver and spleen to sequester iron, increases phagocytosis, inhibits microbe growth, speeds up body repair.

25
4 cardinal signs of inflammation
1. heat 2. swelling 3. redness 4. pain
26
3 stages of inflammation
1. vasodilation: increased permeability of blood vessels. 2. phagocyte migration. 3. tissue repair
27
What is phagocytosis?
the engulfing of a foreign cell
28
Steps of phagocytosis:
1. chemotaxis 2. adherence 3. ingestion
29
What is adherence difficult?
some bacteria have a capsule surrounding them.
30
What is a perforin?
pierces bacterial capsule
31
What are natural killer cells?
next line of defense, lymphocytes that release perforin to look for antigen.
32
What is the magic word?
specific
33
what is the magic number?
2
34
What is an antigen?
any substance that illicit an immune response
35
what is a hapten?
small, foreign, and complex molecules that piggy back on other molecules.
36
what is an epitope?
each antibody recognizes a different part of the protein, called an epitope
37
What is an antigen presenting cell?
displays antigen to helper t cells until it finds one that has matching receptor for antigen complex.
38
what is a cytokine?
protein hormone which regulates normal cell functions
39
What is IgM?
1 antibodies produced. Pentamerous in nature.
40
what is IgG?
Single unit. abundant in serum. Cross the placenta and have the longest half life
41
How does cell mediated immunity resemble Antibody mediated immunity?
requires 2 stimuli and produces interlukin 2
42
How does a Tc cell kill a virus infected cell?
perforins punch holes in the cell membrane, granzymes induce apoptosis
43
What is a primary immune response?
1st time you encounter an antigen.
44
What is a secondary immune response?
memory cells allow for faster immune response
45
How do follicular dendrite cells help maintain immunity?
help b cells become marked as memory cells
46
How does delayed hypersensitivity occur?
2nd time an antigen is encountered, Td cell produces several cytokines that attract and activate macrophages, resulting in an inflammatory reaction.
47
How can we counter the effects of immediate hypersensitivity?
desensitize the person by giving allergen to stimulate IgG antibodies. These tie up the antigen before they can bind with IgE.
48
What is autoimmunity?
the body recognizes itself as foreign
49
What is an autograph?
skin rejection
50
what is an allograph?
heart, lungs, kidney rejection
51
what is an isograph?
allograph with genetic twins
52
what is a xenograph?
between 2 species
53
Natural active immunity?
person gets measels
54
artificial active immunity?
immunization
55
natural passive immunity
baby gets antibodies through milk
56
artificial passive immunity
person receives antibodies through serum