Lymphadenopathy

Question 1

Painful lymphadenopathy most common in

Answer 1

acute infections

Question 2

Painless lymphadenopathy more common in

Answer 2

chronic inflammatory states
metastatic carcinoma
lymphoma

Question 3

HIV infection leads to proliferation of what area of the lymph node

Answer 3

follicular hyperplasia
because dendritic cells are also CD4+
and that’s where they live
they present to B-cells, B-cells in follicles

Question 4

Rheumatoid arthritis lead to proliferation of what area of the lymph node

Answer 4

follicular hyperplasia

Question 5

Paracortical hyperplasia most commonly seen in

Answer 5

viral infections

ie EBV

Question 6

Hyperplasia of medulla/sinus histiocytes seen in

Answer 6

lymph nodes draining tissue w/ cancer

does not necessarily mean cancer is metastasized to node

Question 7

Regions of the lymph node

Answer 7

follicle: B-cells
mantle: area adjacent to follicle
margin: space around mantle (at margin)
* margin often not present in normal nodes