Lung Mechanics Flashcards

1
Q

What is respiration in biochemical and physiological terms

A

Biochemical - Energy producing chemical reactions(converting lactic acid to CO2 and H2O)
Physiological - An interchange of gases between an organism and its environment

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2
Q

What is ventilation

A

The movement of air into and out of the lungs (breathing)

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3
Q

What do the muscles in the lungs do

A

They control the diameter of the airways

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4
Q

What generates pressure differences for breathing

A

Respiratory muscles

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5
Q

What is the active part of breathing

A

inspiration

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6
Q

What allows expiration to be mostly passive

A

The elastic recoil of the lungs that pulls the lungs and diaphragm back to the resting position

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7
Q

What is the main respiratory muscle

A

Diaphragm

Note: not essential for life as other muscles can take over mostly

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8
Q

What effect does activity in the PHRENIC nerves cause in the diaphragm

A

Diaphragm flattens and descends in the chest, causing air to be drawn into the chest

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9
Q

What are the 3 flat muscles that are found in each intercostal space

A

External
Internal
Innermost

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10
Q

What are the roles of the intercostal muscles

A
  • Increase the diameter of the chest to reduce pressure and draw air in.
  • ## Stiffens chest during inspiration preventing it from being sucked in
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11
Q

When are the external intercostals most active and what motion do they control

A

Most active = inspiration

Moves ribs superiorly

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12
Q

When are the internal intercostals most active and what motion do they control

A

Most active = expiration

Moves ribs inferiorly

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13
Q

What is the role of the innermost internals

A

They just act with the internal intercostal muscles

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14
Q

What nerves innervate the intercostal muscles

A

Intercostal nerves

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15
Q

What two types of movement happen during inspiration

A

Pump-handle

Bucket-handle

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16
Q

Describe Pump handle and Bucket handle movements

A

Pump handle - anterior end of each rib is elevated

Bucket handle - diameter of chest increases by rib on either side raised from horizontal position

17
Q

When can expiratory muscles actively contract

A

During high levels of breathing or if airways obstructed by disease

18
Q

What are the most important expiratory muscles

A

Abdominal muscles

19
Q

How do the abdominal muscles help expiration

A

They squeeze the contents of the abdomen up against the diaphragm and force it up into the chest to expel air

20
Q

What is the intrapleural pressure (Ppl)

A

The pressure in the small amount of fluid between the visceral and parietal pleruae

21
Q

Is the intrapleural pressure usually negative or positive with respect to the atmosphere and what effect does this ha ve on the lungs

A

Negative this means the lungs are firmly pressed to the chest wall as the space is airtight

22
Q

What would happen if a puncture wound is made through the thorax

A

Air enters the pleural space, as the pleural pressure is less than the atmosphere, causing pneumothorax. The pressure around the lungs will increase and the lungs may collapse

23
Q

What happens to intrapleural pressure during inspiration and expiration

A

Intrapleural pressure = more negative in inspiration, less negative for expiration
Can become positive in forced expiration

24
Q

What are the elastic properties of the lungs caused by

A

elastic and collagen fibres

surface tension in the alveolar-liquid interface

25
What is lung compliance an expression of
the elasticity of the lungs or how easily they can be stretched
26
What is the main thing that affects lung compliance
Lung diseases
27
How is lung compliance defined
The change in volume produced by a change in pressure across the wall of the structure being investigated - lungs (Cl), chest wall (Cw) or lungs and chest wall (Total compliance Ctot)
28
What is the equation for compliance
Change in Volume/Change in Pressure
29
How would emphysema and fibrosis affect compliance
``` Emphysema = increased Fibrosis = decreased ```
30
Why does emphysema increase lung compliance
It causes destruction of the normal lung architecture, including elastic and collagen fibres, so lungs are mode easily distended and the compliance increases
31
Why does fibrosis decrease compliance
Scar tissue replaces normal interstitial tissue so the lungs become stiffer and compliance decreases
32
How is airway resistance (Raw) defined
This is the resistance to the flow of has within the airways of the lung
33
What is COPD
Chronic Obstructive Pulmonary Disease
34
What is bronchitis
Blocking of airways by secretions
35
What are the 2 types of airway flow
Laminar and Turbulent
36
Describe laminar and turbulent flow
Movement is orderly and streamlined whereas in turbulent flow movement is chaotic
37
What is Poiseuille's Law
Laminar flow is described by this law and is the relationship between driving pressure and flow
38
How is airflow affected by tube radius
Wider tube = less resistance Not directly proportional to change in resistance. radius in equation is r^4. so if radius is halved and everything else is constant, flow is reduced to 1/16.