lower limb disease and DVT Flashcards

1
Q

what is intermittent claudication

A

insufficient blood reaching the muscle while exercising.

muscle ischaemia

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2
Q

risk factors for intermittent claudication

A
smoking
age
diabetes
hypertension
high cholesterol
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3
Q

what are the investigations for intermittent claudication

A

ABPI measurement
ultrasound
angiography (CT, Catheter, MRI)

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4
Q

what is ABPI?

A

ankle BP/ Brachial pressure

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5
Q

what is normal ABPI

A

0.9-1.2

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6
Q

what is an ABPI of claudication

A

0.4-0.85

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7
Q

what is the gold standard investigation for intermittent claudication

A

catheter angiography

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8
Q

what are the treatment options for intermittent claudication

A

angioplasty +/- stent
endarterectomy
bypass

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9
Q

what is critical intermittent claudication

A

insufficient blood reaching the muscle while at rest

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10
Q

what is a DVT

A

formation of thrombi within the lumen of the vessels that make up the deep venous system

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11
Q

where do DVT form

A

predominantly in venous valve pockets and other sites of stasis

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12
Q

what is a distal DVT

A

DVT of the calves

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13
Q

what is a proximal DVT

A

DVT of the popliteal vein or the femoral vein

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14
Q

what are the risk factors for DVT

A
(virchow's triad)
LV dysfunction
immobility/paralysis
obesity
smoking
High BP and cholesterol
surgery
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15
Q

what is a “provoked DVT”

A

a VT with cause, these causes can be transient (e.g surgery or hospitalisation) or continuing (e.g cancer)

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16
Q

what is a “unprovoked DVT”

A

DVT with no identifiable cause. high recurrence rate

17
Q

complications of DVT

A

PE
recurrent DVT
chronic thromboembolic pulmonary hypertension (CTEPH)
post-thrombotic syndrome

18
Q

what is post-thrombotic syndrome

A

A complication of DVT experienced by 1/3 or patients

19
Q

what is post-thrombotic syndrome characterised by

A
pain
oedema
hyperpigmentation
varicose collateral veins
venous ulceration
20
Q

what is chronic thromboembolic pulmonary hypertension (CTEPH)

A

serious complication of DVT experienced by 5% of patients. it is a progressive condition

the original material is replaced by fibrous tissue that is incorporated into the intimate and media of the pulmonary arteries

21
Q

what are the symptoms of chronic thromboembolic pulmonary hypertension (CTEPH)

A

initally asymptomatic followed by progressive SOB and low O2 in the blood

22
Q

what can chronic thromboembolic pulmonary hypertension (CTEPH) lead to

A

RH failure

23
Q

what are the investigations of DVT

A

D-dimer test
well’s score
Ultrasound
CTPA

24
Q

what is the gold standard for DVT

25
what is the first line test for DVT
D-dimer test
26
what would a moderate or high D-dimer test result in
further imaging (CTPA)
27
what would a low/negative D-dimer test suggest
patient is not suffering from PE or DVT
28
what are the pharmacological treatments for DVT
anticoagulants | thrombolysis
29
what are the mechanical interventions for DVT
compression stockings | IVC filters
30
what should you check a patient presenting with a DVT for
thrombophila | cancer
31
if the patient has a DVT due to drug use what drugs should be prescribed
rivaroxaban or fragmin
32
when should thrombolysis be considered in patients with DVT
symptomatic ileofemoral DVT symptoms LEES than 14 days low risk of bleeding life expectancy above 1 year
33
which patients should be given an IVC filter
PROXIMAL DVT
34
what is the treatment for an provoked DVT
LMWH for 5 days | Vit K antagonist within 24hrs and continued for 3 months
35
what is the treatment for unprovoked DVT
LMWH for 5 days Vit K antagonist within 24hrs and continued for minimum 3 months anticoagulation can be continued after 3 months to prevent recurrence