Locally delivered antimicrobials in perio Flashcards
what is the evidence for bacterial cause
acute perio infections
relationship between plaque and gingivitis and periodontitis
efficacy of antibiotics in treating periodontitis
host immunological response
pathogenic potential of plaque bacteria
studies using animal models
what is the mechanical therapy of gingivitis
need to remove deposits on the root surface
what are the limitations of mechanical therapy
poorer treatment with sites that involve furcation
why might mechanical therapy fail to remove all the perio pathogens
sub epithelial gingival tissues
crevicular epithelial tissues
located in connective tissue
subgingival calculus
what is the conc of chlorhexidine
0.2% chlorhexidine gluconate
how much GCF is renewed every hour
0.5 ml which is renewed 40x an hour
what are some local delivery products
actisite periochip dentomycin elyzol atridox arestin
What is a perio chip
2.5 mg chlorhexidine gluconate
Biodegradable geletine chip
What are the benefits of the periochip
Not an antibiotic so cannot get resistance
And will not need to remove it yourself because biodegradable
What is the disadvantages of periochip
Issues with gelatine and religion
What is dentomycin
2% minocycline gel
What is elyzol
25% metronidazole in a monoglyceride and triglyceride gel
What is arestin
1mg of minocycline HCL in encapsulated microspheres
What are the indications for local anti microbial
Pocket depths greater than 5mm
Adjunct you’re mechanical therapy
Non responding sites after initial therapy
Choice of product is influenced by the number of pockets to treat
What are the risks associated with antibiotic resistance
Antibiotic resistance
Effect on gut microbiota
