Local anesthetics (LA) 4

Question 1

Drug has Indirect sympathomimetic, it Inhibit active neuronal uptake of NE?

Answer 1

Cocaine

Question 2

Cocaine is Powerful CNs stimulant causing……………….and………………….

Answer 2

euphoria and hyperthermia

Question 3

Ester local anesthetic not preferred with sulfonamide therapy?

Answer 3

Procaine

because it metabolized by pseudo CHE into PABA which antagonize the effect of
sulfonamide

Question 4

Both drug are Suitable for all techniques of local anesthesia except surface anesthesia?

Answer 4

Procaine and Mepivacaine

Question 5

Has medium duration and Not used now as LA due to high addiction liability?
( mention the drug )

Answer 5

Cocaine

Question 6

Both drug are suitable for all techniques of local anesthesia?

Answer 6

Tetracaine and Lidocaine

Question 7

The most potent of all LAs, the most toxic of all LAs and the longest lasting of all LAs?
(also mention the duration within hour)

Answer 7

Dibucaine
180 minute / 3 Hour

Question 8

Both drug used only in surface anesthesia?
( also mention the cause )

Answer 8

Dibucaine : due to its high toxicity (not injectable)

Benzocaine : limited solubility in water (not suitable for injection)

Question 9

Drug has Anti-arrhythmic effect given by IV route for emergency treatment of ventricular arrhythmia caused by digitalis toxicity?

Answer 9

Lidocaine (lignocaine)

Question 10

Toxic drug to neonates, so not used during delivery?

Answer 10

Mepivacaine

Question 11

Toxicity of the drug is very low due to limited solubility? ( mention the drug )

Answer 11

Benzocaine