Liver functions Flashcards
What are the main functions of the Liver
Oestrogen regulation Albumin Clotting Storage Carb Metabolism Immunity w/Kuppfer cells Detoxification Billirubin Metabolism
Oestrogen regulation is important in what disorders (GPS)
Gyno
Palmar Erythema
Spider Navi
Albumin regulation is indicated in what liver disease (Think Fluid)
Ascites
Oedema
Wilson’s, Haematochromatosis and A1TTD are all types of what liver dysfunction
Liver Storage dysfunction
Bilirubin metabolism is indicated with what liver sign
Jaundice
What is hepaticencephalopathy
Ammonia accumulates and crosses BBB to accumulate in CNS = Confusion
What are the markers of disease in Liver function tests
HIGH Bilirubin
LOW Albumin
HIGH Prothrombin Time/INR
Which non specific enzymes suggest liver damage by spilling into the blood
ALT/AST (Found in liver, heart, kidney and muscles)
GGT
ALP
ALP is raised in what liver diseases
Billiary tree and Bony pathology
GGT is raised in what disease
Alcoholic liver disease
AST:ALT
2 : 1 suggests what disease
Alcoholic liver disease w/ Raised GGT
AST:ALT
4.5 :1 suggests what liver disease
Wilsons
Hyperthyroid
If ALT is greater than AST, what type of liver disease is indicated
Non Alcoholic Fatty Liver Disease