Liver functions Flashcards

1
Q

What are the main functions of the Liver

A
Oestrogen regulation
Albumin 
Clotting
Storage
Carb Metabolism
Immunity w/Kuppfer cells
Detoxification
Billirubin Metabolism
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2
Q

Oestrogen regulation is important in what disorders (GPS)

A

Gyno
Palmar Erythema
Spider Navi

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3
Q

Albumin regulation is indicated in what liver disease (Think Fluid)

A

Ascites

Oedema

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4
Q

Wilson’s, Haematochromatosis and A1TTD are all types of what liver dysfunction

A

Liver Storage dysfunction

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5
Q

Bilirubin metabolism is indicated with what liver sign

A

Jaundice

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6
Q

What is hepaticencephalopathy

A

Ammonia accumulates and crosses BBB to accumulate in CNS = Confusion

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7
Q

What are the markers of disease in Liver function tests

A

HIGH Bilirubin
LOW Albumin
HIGH Prothrombin Time/INR

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8
Q

Which non specific enzymes suggest liver damage by spilling into the blood

A

ALT/AST (Found in liver, heart, kidney and muscles)
GGT
ALP

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9
Q

ALP is raised in what liver diseases

A

Billiary tree and Bony pathology

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10
Q

GGT is raised in what disease

A

Alcoholic liver disease

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11
Q

AST:ALT

2 : 1 suggests what disease

A

Alcoholic liver disease w/ Raised GGT

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12
Q

AST:ALT

4.5 :1 suggests what liver disease

A

Wilsons

Hyperthyroid

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13
Q

If ALT is greater than AST, what type of liver disease is indicated

A

Non Alcoholic Fatty Liver Disease

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