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Liver and Friends > Acute Liver Failure > Flashcards

Acute Liver Failure Flashcards

1
Q

What is Acute liver fail

A

Liver cant regenerate/repair
Irreversibly damaged
Decompensated

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2
Q

What does the typical patient with Acute liver fail look like

A

Hepaticencephalopathy (Confused)
Jaundice w/ Raised IN
Ascites
In patient w/previous normal liver

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3
Q

What is fulminant liver fail

A

Massive hepatocyte necrosis caused by paracetemol overdose

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4
Q

What does jaundice in fulfilmant liver fail normally follow by in terms of symptoms

A

Hepaticencephalopathy(Confusion)

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5
Q

What are the main causes of Acute liver fail

A 
Hepatitis and EBV
Paracetemol and alcohol
Haematochromatosis and Wilsons
HCC
Budd Chiari
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6
Q

What is the typical triad of symptoms in patient with Acute liver fail

A

Jaundice
Coagulopathy (INR >1.5)
HE

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7
Q

What criteria grades Hepaticencephalopathy

A 
West Haven Criteria
1 = altered mood and sleep
2 = lethargy, confusion and asterixis
3 = Confusion marked
4 = Coma
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8
Q

What is Asterixis

A

Hand flapping like a bird

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9
Q

How is Acute liver fail investigated

A

Blood = LFT + Serum tests
Imaging =EEG and Abdo USS
Microbiology

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10
Q

How do the bloods look in LFT of acute liver fail

A 
Raised
-Bilirubin
-PT/INR
-AST/ALT
-Ammonia
Decreased
-Albumin and glucose
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11
Q

What two things are decreased in liver serum for acute liver fail

A

Albumin

Glucose

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12
Q

Why is an EEG used in acute liver fail

A

To grade HE

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13
Q

Why is Abdo USS used in acute liver fail

A

Check Budd Chiari

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14
Q

Why is microbiology used in acute liver fail

A

Rule out infections

  • Blood culture
  • Urine culture
  • Ascitic tap
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15
Q

How is Acute liver fail treated

A

ITU
ABCDE
Fluid and Analgesia

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16
Q

If a patient has acute liver fail due to paracetemol overdoes, they should be treated how

A

Activated charcoal w/ N Acetyl Cysteine

17
Q

What are some complications of Acute liver fail and how are they treated

A 
Raised ICP (IV Mannitol)
HE (Lactulose)
Ascites (Spiranolactone)
Haemorrhage (Vit K)
Sepsis (Sepsis 6)
18
Q

How is HE/Confusion treated

A

Lactulose

19
Q

How is ascites treated

A

Spiranolactone

-Remove fluid

20
Q

What is Budd chiari

A

Occlusion of the hepatic veins (Cant drain liver)

Liver and Friends (27 decks)

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