Hepatitis B Flashcards
What is Hep B (Blood borne)
Liver inflammation caused by dsDNA (HepaDNAvirus)
How can Hep B be transmitted
Needles
Sex
Vertical (From mother)
Horizontal (between children)
Where in the body is HBV found
Semen and Saliva
What are the RF for Hep B
IVDU
MSM
Dialysis
Healthcare professionals
Hep B presents similar to Hep A, how
Prodrome = Malaise, N+V and fever Later = Jaundice, Dark urine, Pale stools
How does Hep B present different to Hep A
Can present w/
- Hepatosplenomegaly
- Hives
- Arthralgia
How is Hep B Treated
SC Pegylated Interferon Alpha 2A
How is Hep B Investigated
HBV DNA Serology
Which HBV Antigen presents 1-6 months after infection
HBVs-Ag
HbsAb presents after 6 months of infection but what does this show
Immunity
If a patient is positive for HBc-Ag, what does this mean
They have been exposed to HBV
A patient acute infected with Hep B presetns w/ what serotype
HBeAg
HBeAb is present in what type of Hep B patient
Chronically ill or cleared
HBeAb decreases infectivity of what serotype
HBeAg (Acute infection)
What is the major complication of HBV in children
Chronic decompensation needing transplant
Which Hepatitis is dependant on Hep B
Hep D
What is Hep D
Liver inflammation caused by ssRNA W/ Hep B
Same as Hep B but Hep D needs Hep B To work