Chronic Liver Fail Flashcards
What is chronic liver fail
Progressive liver disease for >6 months
What are the main causes of Chronic liver fail
Alcoholic liver disease
Non Alcoholic Fatty Liver
Hep B/C/D
What are the main risk factors for Chronic liver fail
Alcohol
Obesity
T2DM
Drugs
What is the physiology of a decompensated liver
Hepatitis = Fibrosis Fibrosis = Cirrhosis Cirrhosis = Decompensation
What can be seen in a patient with decompensated liver fail
Jaundice
HE
Coagulopathy
Ascites ->Oesophageal varices
What score is used to assess Decompensated Chronic Liver fail
Child Pugh Score
What are the three classes of Child Pugh Score for 1 Year survival
A = 100% B = 80% C = 45%
What score is used to model the severity of End Stage Liver disease to plan TRANSPLANT
MELD score
What are the presentations of Chronic liver fail
Jaundice, HE Ascites w/ Portal HTN and Oesophageal Varices Caput medusae Spider Naevi Fetor Hepaticus
What is Caput Medusae
Distended epigastric veins (Think Medusa snakes on stomach)
What is Spider Naevi
RBC Clusters under skin looking like Spiders
What is Fetor Hepaticus
Strong musty breath
What is the Gold standard Investigation for Chronic Liver Fail
Liver Biopsy (Fibrosis vs Cirrhosis)
What investiagtions can be used for Chronic liver fail
Liver Biopsy
LFT
Imaging
Ascitic tap w/ culture
What is the treatment method for chronic liver fail
Prevent Progression = RF Modify Liver transplant (If decompensated) Complication management