Chronic Liver Fail Flashcards

1
Q

What is chronic liver fail

A

Progressive liver disease for >6 months

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2
Q

What are the main causes of Chronic liver fail

A

Alcoholic liver disease
Non Alcoholic Fatty Liver
Hep B/C/D

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3
Q

What are the main risk factors for Chronic liver fail

A

Alcohol
Obesity
T2DM
Drugs

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4
Q

What is the physiology of a decompensated liver

A
Hepatitis = Fibrosis
Fibrosis = Cirrhosis
Cirrhosis = Decompensation
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5
Q

What can be seen in a patient with decompensated liver fail

A

Jaundice
HE
Coagulopathy
Ascites ->Oesophageal varices

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6
Q

What score is used to assess Decompensated Chronic Liver fail

A

Child Pugh Score

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7
Q

What are the three classes of Child Pugh Score for 1 Year survival

A
A = 100%
B = 80%
C = 45%
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8
Q

What score is used to model the severity of End Stage Liver disease to plan TRANSPLANT

A

MELD score

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9
Q

What are the presentations of Chronic liver fail

A
Jaundice, HE 
Ascites w/ Portal HTN and Oesophageal Varices
Caput medusae
Spider Naevi
Fetor Hepaticus
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10
Q

What is Caput Medusae

A

Distended epigastric veins (Think Medusa snakes on stomach)

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11
Q

What is Spider Naevi

A

RBC Clusters under skin looking like Spiders

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12
Q

What is Fetor Hepaticus

A

Strong musty breath

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13
Q

What is the Gold standard Investigation for Chronic Liver Fail

A

Liver Biopsy (Fibrosis vs Cirrhosis)

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14
Q

What investiagtions can be used for Chronic liver fail

A

Liver Biopsy
LFT
Imaging
Ascitic tap w/ culture

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15
Q

What is the treatment method for chronic liver fail

A
Prevent Progression = RF Modify
Liver transplant (If decompensated)
Complication management
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16
Q

What are the complications of Chronic liver fail and how is treated

A

HE = Lactulose
Ascites = Diuretics
Oesophageal Varices rupture
Peritonitis