Liver Flashcards
What vessel is responsible for 25% of hepatic blood flow?
Hepatic Artery
What vessel is responsible for 75% of hepatic arterial flow?
Portal Vein
What modulates the hepatic arterial buffer response?
Adenosine—> but portal venous flow has a major impact on the relative washout of Adenosine
Effect of vasopressin on portal venous vascular resistance?
Decreases vascular resistance
Effect of glucagon on hepatic artery?
Vasodilation
Effect of glucagon on serum calcium?
Hypocalcemia
Components of Child-Pugh Score?
1) Albumin
2) Degree of encephalopathy
3) PT
4) Bilirubin
5) Ascites
6) INR
What are the components of MELD Score?
1) INR
2) Cfeatinine
3) Bilirubin
4) Serum Sodium
5) Dialysis
Why is thrombocytopenia a common finding in cirrhosis?
1) Decreased thrombopoetin
2) Hypersplenism
What lab value is the best indicator of graft function in liver transplant?
INR
After how many days does INR peak following hepatectomy?
1-3 days
After how many days post-hepatectomy does INR normalize?
5-7 days