Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

ITE/Board > General Pharm > Flashcards

General Pharm Flashcards

1
Q

What is the mechanism of Warfarin?

A

Inhibits vitamin K reductase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How much mannitol does each 2 mg vial of dantrolene contain?

A

3 gm of mannitol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the effect of ventilatory response curve for volatiles = to 1 MAC?

A

Rightward parallel shift

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the effect of ventilatory response curve for volatiles > to 1 MAC?

A

Rightward and decreased slope

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the mechanism of analgesia of neuraxial fentanyl?

A

Activation of mu receptors in substantiated gelatinosa in the dorsal horn of the spinal cord

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is hydrocortisone’s effect on nitric oxide synthesis?

A

Inhibits NO synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the mechanism of action of butorphenol?

A

Mixed mu opioid receptor agonist/antagonist plus kappa receptor partial agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

True or false: All opioid receptors provide analgesia?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which opioid receptor is responsible for mitosis, dependence, respiratory depression, sedation, nausea and euphoria?

A

Mu

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which opioid receptor is responsible for respiratory depression and inhibitor of dopamine release, and modulation of mu receptors?

A

Delta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which opioid receptor is responsible for mitosis, diuresis, and dysphoria?

A

Kappa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the function of the opioid receptor ORL-1?

A

Sedation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the mechanism of nalbuphine?

A

Kappa agonist and partial mu antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the mechanism of buprenorphine?

A

mu partial agonist and kappa antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What effect does uremia have on drug protein binding?

A

Decreased binding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What factors increase rate of Hoffman elimination?

A

1) Increased temp

2) Increased pH

17
Q

What is versed use during third trimester associated with?

A

Floppy infant syndrome, neonatal withdrawal

18
Q

What pregnancy category is midazlolam?

A

D

19
Q

What heart rhythm is pathognomic for late advanced digoxin toxicity?

A

Atrial Tach with a 2:1 AV nodal blockade

20
Q

What is the ratio of beta:alpha blockade with labetolol?q

A

7:1

21
Q

How does Nitrous Oxide affect B12?

A

Irreversibly binds to and oxidizes cobalt in B12

22
Q

Onset of labetolol?

A

2-5 minutes

23
Q

What happens when a gas with a higher vapor pressure is filled into a gas canister with a lower sautéed vapor pressure?

A

The delivered % will be higher.

ITE/Board (44 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions