Lipid Synthesis Flashcards
1
Q
What catalyses the sequential attachment of fatty acids to glycerol backbone?
A
Acyltransferase, through an ester bond
2
Q
What is the active form of a fatty acid?
A
A fatty acid attached to coenzyme A derivative (Acyl-CoA)
3
Q
How is the glycerol-3-phosphate backbone made?
A
By reducing DHAP to glycerol-3-phosphate using glycerol-3-phosphate dehydrogenase
4
Q
Which fatty acids are saturated and unsaturated in a phospholipid?
A
The first FA is usually saturated, while the middle one is usually unsaturated
5
Q
How is DAG activated?
A
By adding on CDP (cytidine diphosphate) to form CDP-diacylglycerol; it then reacts with an alcohol to form a phospholipid
