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Question 1

If dietary choline is adequate, how is phos.choline made?

Answer 1

By CTP-phosphatidylcholine cytidyltransferase

Question 2

CCT is especially active is some cancer

Answer 2

YE

Question 3

If choline is deficient how is phos. Choline made?

Answer 3

From phosphatidylethanolamine by methylation with SAM

Question 4

General features of cholesterol?

Answer 4

27 carbons
All c atoms come from acetyl-CoA
Synthesized in the cytosol and ER
4 fused rings, a hydrocarbon tail, OH group on the C-3 and a double bond at C5

Question 5

How is cholesterol synthesis regulated?

Answer 5

Regulation of Cholesterol synthesis occurs at the level of HMG-CoA

Question 6

How is cholesterol stored?

Answer 6

In ester form

Question 7

What is cholesterol a precursor for?

Answer 7

Bile acids, vit d and steroids

Question 8

What is the most common phospholipid In mammals?

Answer 8

Phosohatidyl choline

Question 9

What’s arachidonate a precursor for?

Answer 9

Leukotrienes, thromboxanes, prostacyclin, prostaglandin H2, other prostaglandin

Question 10

Where is cholesterol synthesis regulated?

Answer 10

Inside the cell