Limbic System Flashcards
Anterior Cingulate Cortex (ACC)
Stores long term emotional memory
-operates through ANS through solitary tract and dorsal motor of X
Mid-Cingulate Cortex (MCC)
motivated behavior and response
anterior part
-action during fear
Amygdala
Sensory experience with emotional significance–> prominently FEAR!!
Hypothalamus
Autonomic/hormonal control
Periaqueductal gray (PAG)
Autonomic/skeletal behaviors
- regulates emotional output
- ANS regulation via nucleus of solitary tract/ dorsal motor nuc of X and intermediolateral nuc
Locus Coeruleus (LC)
enhances storage of emotional memories
Uses NE
Dorsal Raphe Nucleus (DRN)
Regulates Mood
Primary emotion
Amygdala, hypothalamus, PAG
- autonomic refelexes
- FEAR
Secondary Emotion
Cortical limbic structures and hippocampus
- object and context dependent and involved conscious processing
- first kiss
LGN/MGN to amygdala
Straight pathway to evoke fear
LC–> uses NE to make sure you remember that fear
Ventromedial Hypothalamus (VMH)
rest and relaxing types of behaviors
Lateral Hypothalamus (LH)
defensive behaviors–> sham rage
Hypothalamic pituitary axis
control parasympathetics and sympathetic via the hypothalamus
Perigenual region
vulnerable to depression
Facial region of ACC
wear emotions on face
-impact facial region
Anterior MCC
fear
Ventral ACC
Sadness
Rostral ACC
Happiness
LC Coordination of motor outputs
- solitary tract/paraventricular nucleus of thalamus
- —mediate HR responses from ACC/central amyg
- PAG–NE F-f
- PVN- drives HPA axis-> NE, ACTH, cortisol
- enhances amygdala processing and memory
Increased Amygdala volume
increase activity-> increase F-F
- high anxiety/depression
Decreased ACC volume
ACC puts breaks on amygdala
-major depression
Reduced glucose metabolism in ACC
Major depression
NE and 5HT
First treatment for mood disorders
SSRIs
Depression
-Dorsal raphe nuclei–produces 5HT to brain
helps Amgy, ACC and insula cortex of limbic system
Deep brain stimulation
stimulates the ACC
