Hypothalamus Flashcards
Two general classes of hypothalamic function
homeostasis and allostasis
5 specific functions of the hypothalamus
Limbic autonomic neuroendocrine Body temperature Energy metabolism/food intake
Neuroendocrine
hormone release from the pituitary regulated by hypothalamus
Body temperature
Transmitted by spinohypothalamic tract
- Anterior Nuclei of hypothalamus- hot sensitive- initiate cooling
- posterior nuclei of hypothalamus- cold sensitive- initiate heating
Preoptic nucleus
Compares input to internal set point temp
Energy metabolism/food intake
Medial hypothalamus and lateral hypothalamus interaction through adrenergic receptors- hunger
Environmental and psychological factors- appetite
Gratification of hunger- satiety- mediated by chemical signals
Anoreixa
Lateral hypothalamic lesions
Advanced degenerative brain dz
systemic medical illness
Psychiatric disorders
Hyperphagia
---increased appetite---- Medial hypothalamic lesions bilateral temporal lobe injury-- Kluver-Bucy Psychiatric disorders Prader-Willi Syndrome
Prader-Willi syndrome
Parental genes missing on chrome 15
- disrupts normal functions of hypothalamus
Causes of feeding disorders
Genetics
Behavior
Environment