limbic Flashcards

1
Q

excitation of cortical activity

A

BFA in pons/midbrain

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2
Q

inhibition of cortical activity

A

medial/ventrla medulla

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3
Q

reticular formation includes BFA; located where and mediates what?

A

in upper pons (midbrian)

mediates arousal and alertness

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4
Q

excitatory NT from BFA

A

acetylcholine

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5
Q

excitatroy NT from substantia nigra

A

dopamine

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6
Q

excitatory NT from locus ceruleus

A

NE

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7
Q

inhibitory NT from raphe nuclei (rostral and ventral divisions)

A

serotonin

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8
Q

Gigantocellular neurons in BFA ascend to ____ and descends to _____.

A

ascends to thalamic nuclei for arousal

descends to spinal cord for tone of antigravity muscles

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9
Q

Parvocellular neuronston intralaminar nuclei (thalamus) does what?

A

modulates pain pathways

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10
Q

What becomes active during REM sleep phase?

A

NE

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11
Q

Locus ceruleus (midbrain) diffuse excitation tot cortex for wakefulness

A

NE

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12
Q

substantia nigra neurons to putamen/caudate control of movement/thoguht

A

dopamine

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13
Q

receptors for excitatory dopamine

A

D1 receptors (inncrease cAMP)

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14
Q

receptors for inhibitory dopamine

A

D2 receptors

decrease in cAMP– rare

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15
Q

ventral tegmental area (VTA) neurons to limbic structures influence..

A

mood

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16
Q

schizophrenia in the VTA

A

lack of focused thought

17
Q

cell bodies in raphe nuclei

A

serotonin

18
Q

dorsal raphe projects to what 4 places

A

thalamus, cortex, cerebellum, BFA

19
Q

serotonin in dorsal raphe inihibts what

A

inhibits cortical activity

inihibition of BFA induces sleep

20
Q

caudal raphe project where?

A

to spinal cord and suppress pain pathways

21
Q

5 functions of the hypothalaus under vegetative control

A
  1. ANS
  2. endocrine system regulation
  3. core body temp
  4. feeding
  5. sleep
22
Q

conscious hypothalamus

A
  1. rage vs fight or flight

2. reward and punishment

23
Q

define limbic system

A

neuronal circuits involved in memory that influence behavior and motivation

24
Q

what does HOME stnad for

A

homeostasis, olfaciton, memory, emotion

25
Q

lateral area of the mid-hypothalamus

A

inhibtiory to adjacent hypothalamic nuclei for reciprocal control of feeding, thirst, rage

26
Q

perventricular area of the mid-hypothalamus

A

septum area and nucleus accumbens (reward center circuitry)

27
Q

3 regions of the hypothalamus

A

anterior (2)
tuberal (6 nuclei)
posterior (2)

28
Q

decrease feeding hormones from the hypothalamus

A

alpha-MSH, leptin, insulin, CCK, peptide YY (PYY)

29
Q

increase feeding hormones from the hypothalamus

A

neuropeptide Y, orexins A & B, ghrelin

30
Q

What 2 nuclei regulate feeding and energy expenditure?

A

arcuate and paraventricular

31
Q

role of anterior nucleus in core temperature

A

heat dissipation

  • sweating
  • panting
  • behavioral adaption
32
Q

role of posteriror nucleus in core temperature

A

heat conservation

  • shivering
  • increase TSH and increased metabolism
  • behavorial adaption
33
Q

Wakefulness innducers orexin A, B located where?

A

lateral hypothalamus

34
Q

wakefulness inducer histamine is located where?

A

posterior hypothalamus

35
Q

Where are the reward centers?

A

lateral and VM nucleus of hypothalamus

others include amygdala and septum

36
Q

Where is the punishment center located?

A

periaqueductal gray (PAG) in midbrain (most potent)