Lignocaine

Question 1

What type is Lignocaine?

Answer 1

Class 1b antiarrhythmic 2% antiarrhythmic 1% local anaesthetic

Question 2

What is Lignocaine MOA?

Answer 2

Blocks Na+ channels reducing the ventricular excitability by blocking Na+ channels during phase 0 = decreased slope of phase 0 and 4

Question 3

What is the preparation of Lignocaine?

Answer 3

Lignocaine 2% = 100 mg in 5ml For IV

Question 4

How does Lignocaine exacerbate ventricular dysrythmias?

Answer 4

May cause bradycardia hypotension heart blocks and asystole by the blocking of Na+ channels leading to reduced conduction and prolonged phase 4

Question 5

What are the indications for Lignocaine?

Answer 5

VT or VF that is unresponsive to Amiodarone

Question 6

What are the oses for Lignocaine 2%

Answer 6

Pt > 16 in refractory VT/VF lig 2% 100mg IV bolus
undiluted 2 dose max 200mg
Pt <16 in refractory VT/VF lig 2% 1mg/kg IV Bolus (max
100mg) undiluted 2 dose max 2 doses.

Question 7

what are the contraindications for Lignocaine?

Answer 7

Allergy or hypersensitivity