leukotriene receptor antagonists

Question 1

what are leukotrienes

Answer 1

substances that are released from the mast cells

Question 2

Zafirlukast action

Answer 2

-selectiveky & competitively block or antagonize receptors for the production of leukotrienes

Question 3

Zafirlukast indications

Answer 3

-prohylaxis & chronic treatment of bronchial asthma in adults & children under 5 years of age & older

Question 4

where is Zafirlukast absorbed

Answer 4

GI tract & liver

Question 5

Zafirlukast caution

Answer 5

-hepatic or renal impairment
-pregnancy/lactation

Question 6

Zafirlukast adverse effects

Answer 6

-headache
-dizziness
-myalgia
-nausea
-diarrhea
-abdominal pain
-elevated LFT
-vomiting
-abdominal pain

Question 7

Zafirlukast drug interactions

Answer 7

-propranolol
-theophylline
-terfenadine
-warfarin might be indicated