ACE-Inhibitors Flashcards
ACE-I names
“Pril” drugs, captopril, lisinopril
action of ACE-I
blocks ACE so that angiotensin I can’t be converted to angiotensin II
-vasodilation: balanced between arteries & veins
-decrease in aldosterone production: loss of sodium and fluid
ACE-I indication
-HTN
-heart failure
-diabetic nephropathy
-post-MI
ACE-I contraindications
-impaired renal function
-pregnancy
-lactation
ACE-I adverse effects
-Angioedema
-Cough (dry, non-productive)
-Electrolyte imbalance (hyperkalemia)
-first dose orthostasis
-Neutropenia (rare)
signs of hyperkalemia
-tingling
-fatigue
-muscle cramps
ACE-I drug to drug interactions
things that worsen kidney function or increase potassium
ACE-I assess/teach
-hypovolemia
-hyperkalemia (paresthesias
-labs
-blood pressure