COMT inhibitors Flashcards
1
Q
names of COMT inhibitors
A
-entacapone
-tolcapone
2
Q
COMT inhibitors method of action
A
enhance the effect of levodopa by blocking its breakdown
3
Q
how is COMT inhibitors excreted
A
urine & feces
4
Q
how is COMT inhibitors metabolized
A
liver, so watch for liver damage
5
Q
side effects of COMT inhibitors
A
-diarrhea
-urine is orange
-watch LFTs
-report muscle pain
-taper the medication
6
Q
can you abruptly stop COMT inhibitors
A
have to taper
