Leukocytes Flashcards
TEM of platelet
When do Rh negative peopel make D antibodies?
post exposure to the Rh antigen
Alpha granules
contain proteins with hemostatic functions
most prevalent and most cross-reactive Rh group
D antigen
Platelet (pointed by red arrow)
hemostasis
integrins anchor to collagen and PM invaginates to change shape for activation
Biggest difference besides lifesan in Basophils vs. Mast cells
basopils still ahve granules but their nucelsu is horse shoe shaped. They also have different receptors
Lymphocytes
B or T lymphocytes.
B: BM, turns into plasma cell
T:BM then Thymus
Big boi lymphocytes are NK cells
inactive (left) and active platelets. precurosor is megakaryocytes
number of days RBCs live
120
Neutrophil
3-5 lobed
motile, (diapedesis)
first line of defense
Eosinophil
allergies and parasites using MBP, ECP, and neurotoxin
Basophil
has heparin and histamine
simialr to mast cells, but life is way shorter.
Immediate asthma, allergins, worms, rheumatoi arthritis
MBP, or major basic protein, granule seen in eosinophils
Monocyte
kidney shape dnucelus
transport version of a macrophage
Lysosomal granules
contain mediators of thrombus dissolution
The erythrocyte maintains its biconcave shape via…
interaction between the cytoskeleton (spectrin) and the integral transmembrane proteins ankyrin and glycophorin
if Rh+ blood is added to Rh- blood that happens to have anti-Rh+ antibodies…
agglutination occurs. Thsi is dangerous in teh case of fetuses with Ph+ and Rh- mommas
antibodies against the D antigen are …
not pre made unless exposed in Rh neg. individuals
Dense core granules
containmediators of vascular tone
