Leukocytes Flashcards

1
Q
A

TEM of platelet

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2
Q

When do Rh negative peopel make D antibodies?

A

post exposure to the Rh antigen

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3
Q

Alpha granules

A

contain proteins with hemostatic functions

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4
Q

most prevalent and most cross-reactive Rh group

A

D antigen

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5
Q
A

Platelet (pointed by red arrow)

hemostasis

integrins anchor to collagen and PM invaginates to change shape for activation

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6
Q

Biggest difference besides lifesan in Basophils vs. Mast cells

A

basopils still ahve granules but their nucelsu is horse shoe shaped. They also have different receptors

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7
Q
A

Lymphocytes

B or T lymphocytes.

B: BM, turns into plasma cell

T:BM then Thymus

Big boi lymphocytes are NK cells

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8
Q
A

inactive (left) and active platelets. precurosor is megakaryocytes

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9
Q

number of days RBCs live

A

120

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10
Q
A

Neutrophil

3-5 lobed

motile, (diapedesis)

first line of defense

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11
Q
A

Eosinophil

allergies and parasites using MBP, ECP, and neurotoxin

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12
Q
A

Basophil

has heparin and histamine

simialr to mast cells, but life is way shorter.

Immediate asthma, allergins, worms, rheumatoi arthritis

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13
Q
A

MBP, or major basic protein, granule seen in eosinophils

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14
Q
A

Monocyte

kidney shape dnucelus

transport version of a macrophage

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15
Q

Lysosomal granules

A

contain mediators of thrombus dissolution

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16
Q

The erythrocyte maintains its biconcave shape via…

A

interaction between the cytoskeleton (spectrin) and the integral transmembrane proteins ankyrin and glycophorin

17
Q

if Rh+ blood is added to Rh- blood that happens to have anti-Rh+ antibodies…

A

agglutination occurs. Thsi is dangerous in teh case of fetuses with Ph+ and Rh- mommas

18
Q

antibodies against the D antigen are …

A

not pre made unless exposed in Rh neg. individuals

19
Q

Dense core granules

A

containmediators of vascular tone