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IM MedEd > Leukemia/Lymphoma > Flashcards

Leukemia/Lymphoma Flashcards

1
Q

Sx of Chronic Leukemia?

A

elevated WBC count (60-100) +/- big ass WBC nuc of smear

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2
Q

2 major types of chronic leukemia

A

CML & CLL

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3
Q

Elevated WBC count, Old man + crushed little lymphocytes on smear

Tx?

A

CLL = Fludarabine or Rituximab

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4
Q

CLL tx

A

Rituximab, Fludarabine

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5
Q

Elevated WBC count in person w/a ton of matured neutrophils + 9:22t

Tx?

A

CML! = Tk-BCL-ABL

Tx: Imatinib

**may progress to AML

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6
Q

Acute Leukemia sx?

A

fever, bones pain, petechia, bleeding, infections, anemia, cells w/small nuc on smear

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7
Q

2 mc acute leukemia?

A

AML, ALL

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8
Q

AML risk factors?

A

exposure to radiation, benzenes & Chemo

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9
Q

Pt w/Bleeding, bruising, petechia, pallor, fever, wonky CBC, +/-Auer rods

dx?

A

Auer Rods = MPO

this is AML

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10
Q

Tx of M3 AML?

A

M3 AML has Auer Rods = Tx w/Vitamin A

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11
Q

Tx of all other AML besides M3?

A

Idarubicin + Ara-C

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12
Q

Risk factors of ALL?

A

down syndrome!

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13
Q

Pediatric pt w/bone pain, bleeding + down syndrome

A

ALL!

Tx w/cyclophosphamide, doxorubicin, vincristine, methrotrexate

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14
Q

Tx of ALL

A

Tx w/cyclophosphamide, doxorubicin, vincristine, methrotrexate

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15
Q

Lymphoma “B” Symptoms

A

fever, night sweats, weight loss

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16
Q

Epstein Fevers?

A

fevers + painfull lymphadenopathy with EtOH & HSM

17
Q

Hodgkins Lymphoma sx?

A

B Symptoms(fever, night sweats, weight loss), Epstein Fevers(fevers + painfull lymphadenopathy with EtOH & HSM), spreads anatomically, usually isolated node

18
Q

Non Hodgkins Lymphoma sx>

A

usually no B shit, spreads hematoginouly, usually multiple nodes

19
Q

Tx of non-hodgkins lymphoma

A

RCHOP: Rituximab, Cyclophosphamide, Hydroxydoxorubicine, Oncovorin, Prednisone

20
Q

Tx of Hodgkins Lymphoma?

A

Mild: ABVD = Adriamycin/Doxo, Bleomycin, Vinblastine, Dacarbazine

Severe: BEACOPP = Bleomycin, Etoposide, Adriamycin/Doxo, Cylcophosphamide, Oncovorin, procarbazine, Prednisone

21
Q

What does RCHOP Stand for? What does it treat?

A

Rituximab, Cyclophosphamide, Hydroxydoxorubicine, Oncovorin, Prednison

Tx: non-hodgkins Lymphoma

22
Q

What does ABVD stand for? What does it treat?

A

Adriamycin/Doxo, Bleomycin, Vinblastine, Dacarbazine

Tx mild hodgkins lymphoma

23
Q

What does BEACOPP stand for what does it treat?

A

Bleomycin, Etoposide, Adriamycin/Doxo, Cylcophosphamide, Oncovorin, procarbazine, Prednisone

Tx severe hodgkins lymphoma

24
Q

Cisplatin side fx?

A

ototox + nephro tox

25
Q

Bleomycin side fx?

A

Plum fibrosis

26
Q

Adriamycin/dox side fx?

A

cardiac shit

27
Q

Vincristine/Vinblastine side fx?

A

peripheral neuropathy

28
Q

Ccyclophosphamide side fx?

A

hemorrhagic cystitis

IM MedEd (24 decks)

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