Cardiac Flashcards
Best drug to lower LDL?
Side fx?
STATIN —| HMG CoA Reductase
Fx: hepatotoxicity,myositis
Drug to lower LDL & Raise HDL but causes flushing…
How do you prevent this side fx?
Niacin –| HSL in fat, decreasing FFA transport
Fx: flushing!, hepatotoxicity
Prevent flushing with asprin!
Best drug to lower total cholesterol? Side fx?
Fibrates –> PPAR-a agonist = increases lipolysis, raising HDL & lowering TC
Fx: gallstones, myositis
Lipid drug that causes diarrhea, constipation, gallstones & bloating? Mechanism of action?
Resins –> increases secretion of bile acids in GI resutling in decreased LDL
Drug that blocks the absorption of cholesterol in the intestines? Fx?
Ezetimibe = decreases LDL
Fx: myositis, contipation, bloating, diarrhea
Who gets a statin?
- Vascular disease
- LDL >/= 190
- LDL 70-189 + 40-75yoa +DM or 10yr risk
- LDL 70-189 + 40-76 w/calculated risk
How often do you check lipids in a person on a statin or w/hypercholesteremia?
ANNUALLY!
*dont need to check liver shit unless symptoms
SIRs Criteria requires 2+ of….
- Temp >38 or <34
- HR >90
- RR>20 or PaCO2 <32
- WBC >12000 or <4000 or >10% bands
How often do you screen for cholesterol levels?
35q5
Screening for osteoporosis?
> 65
Breast cancer screening?
50q2 till 75
Cervical cancer screening?
21q3 till 75
HTN screening?
18q2
Tx of SIRs?
- Give 30cc/kg bolus IVF
- Remove sources of infection
- O2 as needed
- Pressers of bolus fails
- Empiric abx
Treatment fo HF for EVERYBODY?
<2g of salt per day, <2L H2O per day, ACE/ARB, BB