Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hem/Onc > Leukemia > Flashcards

Leukemia Flashcards

1
Q

ALL age?

A

Acute=>

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

CLL/SLL age?

A

> 60 y/o

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

AML age?

A

Median of life=>65 y/o

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CML age?

A

Median age of life=>65 y/o

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

ALL associated with?

A

Down Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

ALL marker?

A

+tdt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

TdT is a? and a marker of?

A

DNA polymerase/marker of pre-T and pre-B cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Thymic mass/Mediastinal mass in a teenager?

A

T-ALL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

B-ALL vs T-ALL?

A

B-ALL=>CD 10, 19, 20 marker; 12;21 translocation

T-ALL=> NO CD 10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

CLL/SLL marker?

A

CD20 and CD5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CLL what cells do you get?

A

Smudge cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Hairy cell leukemia age?

A

Adults; Mature B-Cell tumor in the elderly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Hairy cell leukemia histology?

A

filamentous, hair-like projections

HAIR TRAPs Bugs (B-cell tumor)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Hairy cell leukemia Stain?

A

TRAP (tartrate-resistant acid phosphatase ⊕)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Hairy cell leukemia Tx?

A

cladribine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

In hairy cell leukemia, you get splenomegaly due to?

A

Expansion of the red pulp

17
Q

AML marker?

A

MPO (peroxidase)=>auer rods

18
Q

AML is due to?

A

Alkylating agents

19
Q

AML M3 translocation?

A

t15;17

20
Q

AML Receptor? and Tx?

A

M3 AML subtype responds to all-trans retinoic acid (Vit. A)

21
Q

Acute Monocytic leukemia lacks what thing and has what thing compared to AML?

A

Lacks MPO

Gains Gum lesions

22
Q

Acute megakaryoblastic leukemia associated with>

A

Down Syndrome

23
Q

CML gene?

A

(t[9;22], BCR-ABL)=>increased tyrosine kinase activity

24
Q

CML can lead to?

A

ALL and AML

25
Q

Hallmark of CML?

A

Basophilia

26
Q

CML tx?

A

Imatinib

27
Q

Cells express S-100 (mesodermal origin) and CD1a?

A

Langerhans Cell Histiocytosis

28
Q

Langerhans Cell Histiocytosis histology?

A

birbeck granules

Hem/Onc (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions