Anatomy

Question 1

Neutrophils Like Making Everything Better?

Answer 1

Neutrophils (54–62%) 
Lymphocytes (25–33%) 
Monocytes (3–7%) 
Eosinophils (1–3%) 
Basophils (0–0.75%)

Question 2

Increased Band states indicate?

Answer 2

bacterial infection and CML

Question 3

Lipid A from bacterial LPS binds CD14 on

macrophages to initiate?

Answer 3

Septic Shock

Question 4

Important neutrophil chemotactic agents?

Answer 4

C5a, IL-8, LTB4, kallikrein, platelet-activating factor.

Question 5

Eosinophils produce what? And defend against helminthic infections with?

Answer 5

Produces histaminase and major basic protein (MBP, a helminthotoxin).

Question 6

Causes of Eosinophilia? (NAACP)

Answer 6

Neoplasia
Asthma
Allergic processes
Chronic adrenal insufficiency Parasites (invasive)

Question 7

Basophilia is a sign of?

Answer 7

myeloproliferative disease, particularly CML.

Question 8

How does Mast Cell cause degranulation?

Answer 8

bind the Fc portion of IgE to membrane.

IgE cross-links

Question 9

With macrophages if the infection has resolved, what cytokines for shutting down inflammation?

Answer 9

IL-10 and TNF-alpha

Question 10

With macrophages if there is more work to do, what cytokine?

Answer 10

IL-8

Question 11

Mast Cell are activated by?

Answer 11

1. Tissue Trauma
2. Complement C3a and C5a
3. Cross-linking of cell surface IgE by antigen

Question 12

1st phase of mast cells?

Answer 12

1. Histamine=>vasodilation and vasopermeability at post capillary venules

Question 13

2nd phase of mast cells?

Answer 13

Leukotrienes=>delayed responses

Question 14

Regulatory T-Cell marker?

Answer 14

CD 28

Question 15

Reticulocytes have a bluish tint because?

Answer 15

They have rRNA

Question 16

When do you give RhoGAM?

Answer 16

Third trimester