Lesson 8b: Escherichia coli

Question 1

usually motile with peritrichous flagella and is often fimbriae

Answer 1

E. coli

Question 2

E. coli

Answer 2

its cell wall lipopolysaccharide are used as antigens in serotyping E. coli

Question 3

Serotyping E. coli

Answer 3

✓ Somatic (O)
✓ flagellar (H)
✓ Capsular (K)

Question 4

antigens that are protein in nature

Answer 4

Flagellar (H)

Question 5

antigens that composed of polysaccharides

Answer 5

Capsular (K)

Question 6

are present in many strains and act as adhesins facilitating attachment to mucosal surfaces

Answer 6

Proteinaceous fimbrial (F) antigens

Question 7

Predisposing factors that permit colonization and render animals susceptible to the development of clinical disease include;

Answer 7

age, immune status, nature of diet and heavy exposure to pathogenic strains

Question 8

Virulence factors of pathogenic strains of E. coli

Answer 8

capsules, endotoxin, enterotoxin, structure responsible for adherence and colonization

Question 9

interfere with phagocytosis and with the antibacterial effectiveness of the complement system

Answer 9

Capsule

Question 10

it released upon lysis or death of the bacteria, produce pyrogenic activity, endothelial damage leading to disseminated intravascular coagulation

Answer 10

endotoxin

Question 11

are significant events in septicaemia

Answer 11

endotoxic shock

Question 12

allow attachment to mucosal surfaces and facilitates colonization by diminishing the expulsive effects of peristalsis and the flushing effect of urine

Answer 12

Fimbrial adhesins

Question 13

Fimbrial adhesins have been identified namely;

Answer 13

K88 (F4, K99 (F5), 987 (F6), F18 and F41

Question 14

the most common adhesin present in strains of E. coli infecting pigs is?

Answer 14

K88

Question 15

adhesins occurs in calves

Answer 15

F41

Question 16

adhesins occurs in calves and lambs

Answer 16

K99

Question 17

What receptors are found only in older piglets?

Answer 17

F18

Question 18

strains that are important in post weaning diarrhoea and oedema disease

Answer 18

F18+

Question 19

term of adhesin that associated with attaching and effecting E. coli

Answer 19

Intimin

Question 20

produce characteristic attaching and effecting lesions in which the bacteria are intimately adherent to the host epithelial cell membrane with marked rearrangement of the cytoskeleton

Answer 20

AEEC

Question 21

the pathological effects of infection with pathogenic E. coli, other than those attributed to endotoxin, derive mainly from the production of?

Answer 21

enterotoxins, shigatoxins or cytotoxic necrotizing factors

Question 22

Two types of enterotoxins

Answer 22

✓ heat-labile (LT)
✓ heat-stable (ST)

Question 23

found most in pigs, induces hypersecretion of fluid into the intestine through stimulation od adenylate cyclase activity

Answer 23

Heat-labile (LT1)

Question 24

has been demonstrated in some ETEC strains isolated from cattle

Answer 24

heat-labile (LT2)

Question 25

isolated from porcine, bovine, and human specimens

Answer 25

STa

Question 26

this toxin stimulates fluid and electrolyte secretion into the small intestine and inhibits fluid absorption from the intestine by increasing intracellular guanosine monophosphate

Answer 26

STa

Question 27

also causes secretion of chloride and bicarbonate ions as well as inhibition of absorption sodium ions

Answer 27

STb

Question 28

affects newborn calves, lambs and piglets. common under intensive systems of management due to build-up of infection in the environment

Answer 28

Enteric colibacillosis

Question 29

Important virulence factor for Enteric colibacillosis are?

Answer 29

fimbrial adhesins such K99 and K88

Question 30

are of particular importance in neonatal diarrhoea

Answer 30

K88 and K99

Question 31

they produce enterotoxins which stimulate hypersecretory diarrhoea and interfere with fluid absorption

Answer 31

Enteric colibacillosis

Question 32

relatively frequent in calves, lambs and poultry. Often presents as an acute fatal disease with many of the clinical signs attributable to the action of endotoxin

Answer 32

Colisepticaemia

Question 33

In poultry, colisepticaemia the form of the disease is called?

Answer 33

coligranuloma (Hjarre's disease)

Question 34

characterised by ironic inflammatory changes resembling tuberculous lesions which are encountered at postmortem examination in laying henz

Answer 34

Coligranuloma (Hjarre's disease)

Question 35

occurs 1 to 2 weeks after weaning in rapidly growing pigs. The aetiology of the disease is complex which includes E. coli, with nutritional and environmental changes and other stress factors contributing to its development

Answer 35

Edema disease in pigs

Question 36

Isolated noninvasive E. coli strains replicate in the tract and produce a?

Answer 36

shigatoxin (ST2e)

Question 37

absorbed into the bloodstream and damages endothelial cells with consequence perivascular oedema

Answer 37

shigatoxin (ST2e)

Question 38

occurs in within a week or two after weaning often following changes in feeding regimens or in management and with possible involvement of rotaviruses.

Answer 38

Post-weaning diarrhea of pigs

Question 39

infection of the mammary glands of cows and sows by members of the Enterobacteriaceae, including E. Coli. The acute form of the disease is characterized by endotoxaemia and can be life threatening

Answer 39

coliform mastitis

Question 40

Urogenital tract infections

Answer 40

Opportunistic ascending infections of the urinary tract by certain uropathogenic strains of E. coli result in cystitis, especially in bitches.

Question 41

They invade the bloodstream following infection of the intestines, lungs, or umbilical tissues

Answer 41

E. coli