Lesson 5: Getting Started with Animal Work Flashcards
The groups of people you should get to know when planning work with vertebrae animals?
*CARE
*IACUC staff, chairperson, and committee
*Animal facility manager
Based on the AWR, if a little bit of pain or distress is caused to the research animal, then what must occur?
An attending veterinarian must occur in planning those procedures. Then a consultation between the PI and vet. This is done before the IACUC meeting.
eSirius protocol management system?
A web based system for managing the submission, review and approval of animal protocols at Cornell.
What are points to consider when asking for approval to conduct research on a vertebrate?
If you are studying a human or anima disease or health concern:
*The disease
*What causes it
*What therapy is currently used to treat it
*How the proposed animal experiments might improve health or prevent human or animal pain and suffering.
*Because there are non-scientists in IACUC, part of the response should be explained using language that a high school student should understand.
*Avoid complex scientific language
*Make sure to explain and define medical terms and abbreviations the first time when using them.
When explaining experimental design, what must clearly be stated?
Treatment, control group, and brief description of animal use.
Least sentient (aware) species should be used. Hierarchy?
Apes (chimps, orangutans, gorillas)
Monkeys (baboons, macaques, marmosets, tamarins)
Larger animals commonly kept as pets such as dogs and cats
Larger agricultural animals such as pigs and goats
Rabbits
Rodents (guinea pigs, hamsters, rats, mice)
Non-mammalian vertebrates (poultry, amphibians, reptiles, fish)
Cephalopods and gastropods (octopus, squids, slugs)
Other invertebrates (insects, arachnids, worms)
Single cell organisms (yeast, bacteria, etc.)
Does IACUC ask for certain number of animals and need a justification for why?
yes, yes
When justifying animal numbers, what should be used?
A statistical analysis.
When deciding the number of animals used, what should be the most important criteria?
Number to not minimize the number of animals but to determine the right number for obtaining valid results.
Enrichment for animals?
*Social contact
*Control over the environment
*Food
Housing social animals?
They should be housed in pairs or groups unless scientific health or behavioural considerations prevent it.
Animal protocol application will ask you to describe ____ that you propose to use in animals.
Procedures, all must comply with standards from ACUPs.
