Leishmania Flashcards

1
Q

Types and causes

A

tropica: cutan
braziliensis: mucocutan
donovani: visceral
infantum: visceral and cutan
chagasi: visceral and cutan

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2
Q

To diagnose leishmania

A

amastigote in smears and scrapings

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3
Q

Type of development

A

ALWAYS indirect

IC development in histiocytes/macrophages

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4
Q

What form are found in vertebrates/reservoirs?

A

amastigotes

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5
Q

What form is found in the biological vector?

A

Promastigote

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6
Q

What is the intermediate host

A

The female sandfly!
promastigotes go out in the saliva
Blood-sucking

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7
Q

Difference between promastigotes and amastigotes

A

Pro: are thinner and smaller (than trypanosoma?)
EC in the salivary glands

Amas: Divided IC in the macrophages
found in smears/scrapings
no flagella

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8
Q

Patho signs: cutaneous

A

Alopecia
Dermatitis
Ulceration

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9
Q

Patho signs: mucocutaneous

A

most dangerous!! because inside the oral cavity the mouth can swell and cause suffocation

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10
Q

Patho signs: Visceral

A
Intermittent fever
Enlargement of lymph nodes 
Cachexy
Anaemia
Ataxia 
PU/PD
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