Leishmania Flashcards
Types and causes
tropica: cutan
braziliensis: mucocutan
donovani: visceral
infantum: visceral and cutan
chagasi: visceral and cutan
To diagnose leishmania
amastigote in smears and scrapings
Type of development
ALWAYS indirect
IC development in histiocytes/macrophages
What form are found in vertebrates/reservoirs?
amastigotes
What form is found in the biological vector?
Promastigote
What is the intermediate host
The female sandfly!
promastigotes go out in the saliva
Blood-sucking
Difference between promastigotes and amastigotes
Pro: are thinner and smaller (than trypanosoma?)
EC in the salivary glands
Amas: Divided IC in the macrophages
found in smears/scrapings
no flagella
Patho signs: cutaneous
Alopecia
Dermatitis
Ulceration
Patho signs: mucocutaneous
most dangerous!! because inside the oral cavity the mouth can swell and cause suffocation
Patho signs: Visceral
Intermittent fever Enlargement of lymph nodes Cachexy Anaemia Ataxia PU/PD