Lectures 13&14 Intro To Blood & Blood Cells Flashcards
Is blood considered an organ or tissue?
Blood is a liquid tissue
What is hemophilia caused by?
Not enough clotting factors
How many liters of blood does an average human have?
5L
What is the PH and density of blood?
7.4 (+-.05) 1.057(+-.009)
What are erythrocytes?
RBC’s
What are leukocytes?
WBC’s
What are Thrombocytes?
Platelets
What must be added before centrifuging blood?
Anticoagulants Cellular elements are separated from plasma
List the elements after centrifugation and their percentage composition
Plasma (55%) RBC’s 45% WBC’s and platelets <1%
What are the constituents of blood plasma and percentage composition?
- Water (90-92%- Maintain blood volume. Transports molecules
1. ) Plasma proteins (7-8%)- Maintain Osmotic pressure &PH
Albumin- Transports bilirubin
Globulins- Transports Cholesterol, fight infection
Fibrinogens- Blood clotting
- Salts& ions <1%
Na+ &K+ &Cl- maintain membrane permeability
Mg2+ &Ca2+ - aid in metabolism
HCO3-
All salts- maintain osmotic pressure
List the constituents of plasma and the source in the body
- Water (90-92%) Absorbed from Intestine
- Plasma Proteins (7-8&) Liver
- Salts, Ions Absorbed from intestine
Where is the source of Nitrogenous wastes, and where are they excreted?
Made in Liver, excreted by Kidneys
What is the function of Harmones and Vitamines?
Aid in Metabolism
What is the size, color, and shape of RBC’s?
7-8μm in diameter
Bright red to dark purple
Biconcave in shape
What is a unique feature of RBC’s?
Mature RBC’s lack nucleus
Why is haemoglobin an excellent transporter of O2 & CO2?
it contains harem, Fe2+
contains no nucleus ∴ more SA for O2
What is the conc of RBC’s in blood, and the number in our body?
25 trillion
4-6x10^6/mm3
What are the number of haemoglobin molecules in an RBC?
250 million- bright red protein
What is haemoglobin made out of?
4 Globin protein chains
2 alpha 2 beta
Iron for each Globin (2 O2 molecules each Globin)