Lecture: thyroid

Question 1

hypothyroidism s/s

Answer 1

apathy, lethargy, muscle aches and weakness, constipation, extreme fatigue, brittle hair and nails, hair loss, intolerance to cold, heavy menses

Question 2

Levothyroxine

Answer 2

DOC for hypothyroidism
half life = 7 days so 1 month for steady state
AE thyrotoxicosis

Question 3

thyroid responsible for:

Answer 3

energy use (metabolism, heat),
stimulates the heart,
promotes growth and development

Question 4

hyperthyroidism s/s

Answer 4

Graves disease

tremors, tachycardia, muscle wasting, diarrhea, weight loss, fine straight hair, amenorrhea (light/no menses), intolerance to heat, sometimes exophthalmos and goiter

Question 5

thyroid storm

Answer 5

profound hyperthermia (105*)
severe tachycardia
restlessness, agitation
tremors
unconsciousness, como, hypotension

tx: methimazole, beta blocker, glucocorticoids, iv
sedation, cooling

Question 6

methimazole

Answer 6

1st line for hyperthyroid

PTU next

Question 7

radioactive iodine

Answer 7

delayed effect 2-3 months

AE: hypothyroidism

Question 8

Lugol’s solution (non-radioactive iodine)

Answer 8

used to suppress thyroid function before thyroidectomy