lecture: bipolar drugs

Question 1

Bipolar disorder is treated with (3)

Answer 1

mood stabalizers (lithium, vlaproate, etc), antipsychotics, anditdepressants

Question 2

___ is the DOC for bipolar disorder.

Answer 2

lithium

Question 3

The renal system treats lithium like ___. (So if it drops, the body will retain lithium). Therefore all interactions are related to the sodium excretion by the kidneys. Drug interactions include:

Answer 3

sodium

diuretics, NSAIDs, anticholinergics

Question 4

Lithium plasma levels are 0.8-1.4 mEq/L. The trough levels should be checked ___.

Answer 4

in the morning (12 hours after evening dose and before next dose)

Question 5

____ are used to treat manic episodes in bipolar disorder.

Answer 5

Antiepileptic drugs (mood stabilizers)
These include divalproex sodium, carbamazepine, and lamotrigine.

Question 6

___ are used acutely to control symptoms during manic episodes. They are used long term to help stabilize mood. The can be combined with mood stabilizers (lithium, divalproex sodium, and carbamazapine).

Answer 6

Antipsychotics

These include:
risperidone  [Risperdal]
aripiprazole  [Abilify]
olanzapine  [Zyprexa]
quetiapine  [Seroquel]
ziprasidone [Geodon]
cariprazine  [Vraylar]
asenapine  [Saphris]
lurasidone  [Latuda]