Lecture: ADH

Question 1

ADH is also known as ____.

Answer 1

Vasopressin

because it can cause vasoconstriction at high doses.

Question 2

Too little ADH leads to ___

Answer 2

Diabetes Insipidus.

S/S: large volumes of dilute urine, polydipsia (increased thirst)

Question 3

Diabetes Insipidus (too little ADH) is treated with ___

Answer 3

desmopression (synthetic vasopressin)

Question 4

Adverse effects of desmopressin include:

Answer 4

water intoxication.

Tell patients to reduce water intake, especially in heart failure.

Question 5

Too much ADH leads to ___

Answer 5

SIADH (syndrome of inappropriate antidiuretic hormone)

Question 6

The biggest danger of SIADH is ___

Answer 6

hyponatremia which can lead to cerebral edema

Question 7

SIADH is treated with __

Answer 7

-vaptans (vasosupression antagonists)

conivaptan, tolvaptan

Question 8

-Vaptan administration nursing implications

Answer 8

don’t correct more than 12 mEq/L per 24 hrs.

Tx too quickly = osmotic demyelination!